Highly selective electrochemical detection of serotonin on polypyrrole and gold nanoparticles-based 3D architecture

被引:84
|
作者
Tertis, Mihaela [1 ]
Cernat, Andreea [1 ]
Lacatis, Daniela [1 ]
Florea, Anca [1 ]
Bogdan, Diana [2 ]
Suciu, Maria [2 ]
Sandulescu, Robert [1 ]
Cristea, Cecilia [1 ]
机构
[1] Iuliu Hatieganu Univ Med & Pharm, Fac Pharm, Dept Analyt Chem, 4 Louis Pasteur St, Cluj Napoca 400349, Romania
[2] Natl Inst Res & Dev Isotop & Mol Technol, 67-103 Donat St, Cluj Napoca 400293, Romania
关键词
Serotonin; Polypyrrole; Gold nanoparticles; Electropolymerization; GLASSY-CARBON ELECTRODE; QUARTZ-CRYSTAL MICROBALANCE; GRAPHITE ELECTRODE; GRAPHENE-OXIDE; ASCORBIC-ACID; GAS-PHASE; COMPOSITE; DOPAMINE; SENSOR; PYRROLE;
D O I
10.1016/j.elecom.2016.12.015
中图分类号
O646 [电化学、电解、磁化学];
学科分类号
081704 ;
摘要
A new customized platform based on electrochemically generated polypyrrole nanoparticles decorated with gold nanoparticles was used for the highly selective and sensitive electrochemical detection of serotonin. The composite surface manifested improved properties attributed to both modifiers: an fix-leased active surface area due to the polypyrrole nanostructure and a catalytic effect towards analyte detection from the noble metal. The material was applied to the detection of serotonin in serum samples, in the presence of interfering species. The analytical performance was 320 times better than that of the bare electrode, underlining the advantages of this tailored hybrid surface. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码:43 / 47
页数:5
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