Non-enzymatic sensor for determination of glucose based on PtNi nanoparticles decorated graphene

被引：20
|
作者：
Li, Risheng [1 ,2 ,3 ]
Deng, Xu [4 ,5 ]
Xia, Longfei [1 ,2 ,3 ]
机构：
[1] Shaanxi Prov Land Engn Construct Grp Co Ltd, Xian 710075, Peoples R China
[2] Shaanxi Prov Land Engn Construct Grp Co Ltd, Inst Land Engn & Technol, Xian 710075, Peoples R China
[3] Minist Nat Resources, Key Lab Degraded & Unused Land Consolidat Engn, Xian 710075, Peoples R China
[4] Shaanxi Normal Univ, Key Lab Analyt Chem Life Sci Shaanxi Prov, Xian 710062, Peoples R China
[5] Shaanxi Normal Univ, Key Lab Med Resources & Nat Pharmaceut Chem, Minist Educ, Xian 710062, Peoples R China
来源：
SCIENTIFIC REPORTS | 2020年 / 10卷 / 01期
关键词：
CAPACITY ANODE MATERIAL; GOLD NANOPARTICLES; OXIDE; NANOSTRUCTURES; ALLOY; ACID;
D O I：
10.1038/s41598-020-73567-2
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Diabetes has become a universal epidemic in recent years. Herein, the monitoring of glucose in blood is of importance in clinical applications. In this work, PtNi alloy nanoparticles homogeneously dispersed on graphene (PtNi alloy-graphene) was synthesized as a highly effective electrode material for glucose detection. Based on the modified PtNi alloy-graphene/glass carbon (PtNi alloy-graphene/GC) electrode, it is found that the PtNi alloy-graphene/GC electrode exhibited excellent electrocatalytic performance on glucose oxidation. Furthermore, the results from amperometric current-time curve show a good linear range of 0.5-15 mM with the limit of detection of 16 uM (S/N=3) and a high sensitivity of 24.03 uAmM(-1) cm(-2). On account of the good selectivity and durability, the modified electrode was successfully applied on glucose detection in blood serum samples.
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页数：8
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