How does hepcidin hinder ferroportin activity?

被引：18
|
作者：
Zhang, De-Liang [1 ]
Rouault, Tracey A. [1 ]
机构：
[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Bethesda, MD 20892 USA
来源：
BLOOD | 2018年 / 131卷 / 08期
关键词：
INTRACELLULAR IRON; CELLS; MACROPHAGES; EXPRESSION;
D O I：
10.1182/blood-2018-01-824151
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In this issue of Blood, Aschemeyer et al found that hepcidin bound to the central cavity of ferroportin (Fpn) and occluded its iron export activity, thereby revealing a previously unrecognized mechanism for Fpn regulation.(1)
引用
收藏
页码：840 / 842
页数：5
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