In vivo evaluation of human skin anisotropy by polarization-sensitive optical coherence tomography

被引:50
|
作者
Sakai, Shingo [1 ]
Yamanari, Masahiro [2 ]
Lim, Yiheng [2 ]
Nakagawa, Noriaki [1 ]
Yasuno, Yoshiaki [2 ]
机构
[1] Kanebo Cosmet Inc, Innovat Beauty Sci Lab, Odawara, Kanagawa 2500002, Japan
[2] Univ Tsukuba, Computat Opt Grp, Tsukuba, Ibaraki 3058573, Japan
来源
BIOMEDICAL OPTICS EXPRESS | 2011年 / 2卷 / 09期
关键词
DERMAL COLLAGEN FIBER; LANGERS LINES; TENSION LINES; MICROSCOPY; QUANTIFICATION; BIREFRINGENCE;
D O I
10.1364/BOE.2.002623
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We performed an in vivo three-dimensional analysis of anisotropic changes in the dermal birefringence of mechanically deformed human skin using polarization-sensitive optical coherence tomography (PS-OCT). The papillary-dermal birefringence of the forehead increased significantly when the skin was shrunk parallel to the body axis, and decreased significantly when the skin was shrunk perpendicular to the body axis. En-face images of the papillary-dermal birefringence revealed variations among individual subjects, and that both shrinking parallel to and stretching in perpendicular to the body axis promoted the formation of macro rope-like birefringent domains. We found that PS-OCT is useful for understanding anisotropic properties of collagen structure in the skin. (C) 2011 Optical Society of America
引用
收藏
页码:2623 / 2631
页数:9
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