Precise and programmable manipulation of microbubbles by two-dimensional standing surface acoustic waves

被引：66

作者：

Meng, Long ^{[1
]}

Cai, Feiyan ^{[1
]}

Chen, Juanjuan ^{[1
]}

Niu, Lili ^{[1
]}

Li, Yanming ^{[1
]}

Wu, Junru ^{[2
]}

Zheng, Hairong ^{[1
]}

机构：

[1] Chinese Acad Sci, Paul C Lauterbur Res Ctr Biomed Imaging, Inst Biomed & Hlth Engn, Shenzhen Inst Adv Technol, Guangzhou 518055, Guangdong, Peoples R China

[2] Univ Vermont, Dept Phys, Burlington, VT 05405 USA

来源：

APPLIED PHYSICS LETTERS | 2012年 / 100卷 / 17期

基金：

美国国家科学基金会;

关键词：

IN-VITRO; DELIVERY; VIVO;

D O I：

10.1063/1.4704922

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

A microfluidic device is developed to transport microbubbles (MBs) along a desired trajectory in fluid by introducing the phase-shift to a planar standing surface acoustic wave (SSAW). The radiation force of SSAW due to the acoustic pressure gradient modulated by a phase-shift can move MBs to anticipated potential wells in a programmable manner. The resolution of the transportation is approximately 2.2 mu m and the estimated radiation force on the MBs is on the order of 10(-9) N. This device can be used for manipulation of bioparticles, cell sorting, tissue engineering, and other biomedical applications. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4704922]

引用

页数：4

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