The Role of Chicken Prolactin, Growth Hormone and Their Receptors in the Immune System

被引:4
|
作者
Mo, Guodong [1 ,2 ,3 ]
Hu, Bowen [1 ,2 ,3 ]
Wei, Ping [4 ]
Luo, Qingbin [1 ,2 ,3 ]
Zhang, Xiquan [1 ,2 ,3 ]
机构
[1] South China Agr Univ, Coll Anim Sci, Guangdong Prov Key Lab Agroanim Genom & Mol Breedi, Guangzhou, Peoples R China
[2] Minist Agr, Key Lab Chicken Genet Breeding & Reprod, Guangzhou, Peoples R China
[3] South China Agr Univ, State Key Lab Conservat & Utilizat Subtrop Agrobio, Guangzhou, Peoples R China
[4] Guangxi Univ, Inst Poultry Sci & Hlth, Nanning, Peoples R China
基金
中国国家自然科学基金;
关键词
chicken; growth hormone; immune response; prolactin; receptor; RECOMBINANT BOVINE SOMATOTROPIN(R); VASOACTIVE-INTESTINAL-PEPTIDE; LEUKOSIS VIRUS-INFECTION; NEWCASTLE-DISEASE VIRUS; I INTERFERON EXPRESSION; PITUITARY-ADRENAL AXIS; INDUCED LEUCINE-ZIPPER; INFLAMMATORY RESPONSE; GENE POLYMORPHISMS; MOLECULAR-CLONING;
D O I
10.3389/fmicb.2022.900041
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Prolactin (PRL) and growth hormone (GH) exhibit important roles in the immune system maintenance. In poultry, PRL mainly plays its roles in nesting, hatching, and reproduction, while GH is primarily responding to body weight, fat formation and feed conversion. In this review, we attempt to provide a critical overview of the relationship between PRL and GH, PRLR and GHR, and the immune response of poultry. We also propose a hypothesis that PRL, GH and their receptors might be used by viruses as viral receptors. This may provide new insights into the pathogenesis of viral infection and host immune response.
引用
收藏
页数:12
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