Expanding the toolbox for 3D genomics

被引:0
|
作者
Stadhouders, Ralph [1 ,2 ]
机构
[1] Erasmus MC, Dept Pulm Med, Rotterdam, Netherlands
[2] Erasmus MC, Dept Cell Biol, Rotterdam, Netherlands
关键词
CHROMOSOME CONFORMATION; ORGANIZATION; DOMAINS;
D O I
10.1038/s41588-018-0112-1
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The ability to visualize and study the 3D folding of chromosomes in cells has been propelled forward by several major technological advances in the past two decades. Two new studies now further expand the scientific toolbox for studying chromosome conformation by providing novel methodologies for accurate mapping of genome topology and predicting the topological effects of genomic structural variation.
引用
收藏
页码:634 / 635
页数:2
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