Proteomic investigation of human cystic echinococcosis in the liver

被引：13

作者：

Longuespee, Remi ^{[1
,2
]}

Casadonte, Rita ^{[1
]}

Kriegsmann, Mark ^{[2
]}

Wandernoth, Petra ^{[3
]}

Lisenko, Katharina ^{[4
]}

Mazzucchelli, Gabriel ^{[5
]}

Becker, Michael ^{[6
]}

Kriegsmann, Joerg ^{[1
,3
,7
]}

机构：

[1] Proteopath GmbH, Max Planck Str 17, D-54296 Trier, Germany

[2] Heidelberg Univ, Inst Pathol, Neuenheimer Feld 224, D-69120 Heidelberg, Germany

[3] Mol Pathol Trier, Max Planck Str 17, D-54296 Trier, Germany

[4] Heidelberg Univ, Dept Internal Med 5, Neuenheimer Feld 410, D-69120 Heidelberg, Germany

[5] Univ Liege, GIGA Res, Syst Biol & Chem Biol, Mass Spectrometry Lab LSM, Allee 6 aoUt 11, B-4000 Liege, Belgium

[6] Bruker Daltonik GmbH, Fahrenheitstr, D-28359 Bremen, Germany

[7] MVZ Histol Cytol & Mol Diagnost Trier, Max Planck Str 5, D-54296 Trier, Germany

来源：

MOLECULAR AND BIOCHEMICAL PARASITOLOGY | 2017年 / 211卷

关键词：

Histoproteomics; Cystic echinococcosis; Laser microdissection; Parasitic disease; MALDI IMS; PARAFFIN-EMBEDDED TISSUE; IMAGING MASS-SPECTROMETRY; GRANULOSUS METACESTODE; LARVAL; TOOL; INFECTION; REVEALS; CANCER;

D O I：

10.1016/j.molbiopara.2016.12.002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cystic echinococcosis (CE) is a pandemic infectious disease caused by the tapeworm Echinococcus granulosus that forms cysts in different organs such as lungs and liver. Imaging examination and serological tests have some drawbacks such as low sensitivity. In this study, we used an up-to-date workflow of laser microdissection-based microproteomics and matrix-assisted laser desorption/ionization time-of-flight imaging mass spectrometry in order to depict the proteomic pattern of CE in the liver. This investigation revealed specific markers of a parasitic cyst in liver. This proteomic pattern could facilitate diagnosis of CE in the future. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：9 / 14

页数：6

共 50 条

[1] Cystic echinococcosis of the liver
Aziz, Hassan
Seda, Peyton
Aswani, Yashant
Gosse, Matthew D.
Krishnakumari, Aparna Joshi
Pawlik, Timothy M.
JOURNAL OF GASTROINTESTINAL SURGERY, 2025, 29 (03)
[2] Principles of the surgical approach in human liver cystic echinococcosis
Perdomo, R
Alvarez, C
Monti, J
Ferreira, C
Chiesa, A
Carbo, A
Alvez, R
Grauert, R
Stern, D
Carmona, C
Yarzabal, L
ACTA TROPICA, 1997, 64 (1-2) : 109 - 122
[3] LIVER REGENERATION IN CYSTIC ECHINOCOCCOSIS
KOURIAS, B
ACTA HEPATO-SPLENOLOGICA, 1968, 15 (03): : 189 - &
[4] Major Liver Resections in cystic Echinococcosis of the Liver
Nikolic, A.
Rauchfuss, F.
Settmacher, U.
CHIRURG, 2018, 89 (09): : 735 - 735
[5] Major Liver Resections in cystic Echinococcosis of the Liver
Nikolic, A.
Rauchfuss, F.
Settmacher, U.
CHIRURG, 2019, 90 : S64 - S64
[6] Surgical management of cystic echinococcosis of the liver
Berto, Cesar G.
Liou, Peter
Coyle, Christina M.
Emond, Jean C.
CURRENT OPINION IN INFECTIOUS DISEASES, 2023, 36 (05) : 348 - 352
[7] Cystic echinococcosis of the liver: A primer for hepatologists
Rinaldi, Francesca
Brunetti, Enrico
Neumayr, Andreas
Maestri, Marcello
Goblirsch, Samuel
Tamarozzi, Francesca
WORLD JOURNAL OF HEPATOLOGY, 2014, 6 (05) : 293 - 305
[8] Update on Treatment for Cystic Echinococcosis of the Liver
Enrico Brunetti
Liliana Praticò
Andreas Neumayr
Marcello Maestri
Francesca Tamarozzi
Current Treatment Options in Infectious Diseases, 2016, 8 (3) : 153 - 164
[9] Morphological Characteristics of Alveolar and Cystic Echinococcosis Lesions in Human Liver and Bone
Barth, Thomas F. E.
Casulli, Adriano
PATHOGENS, 2021, 10 (10):
[10] Accidentally Discovered Cystic Echinococcosis of the Liver
Elkhouly, Mohamed A.
Attar, Bashar M.
Elkafrawy, Ahmed A.
Vohra, Ishaan
Salazar, Miguel
Mutneja, Hemant
Mishra, Satya
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2019, 114 : S1292 - S1292

← 1 2 3 4 5 →