Cyr61/CCN1 affects the integrin-mediated migration of prostate cancer cells (PC-3) in vitro

被引：14
|
作者：
Schmitz, Patrick [1 ]
Gerber, Ursula [1 ]
Juengel, Eva [2 ]
Schuetze, Norbert [3 ]
Blaheta, Roman [2 ]
Bendas, Gerd [1 ]
机构：
[1] Univ Bonn, Dept Pharm, D-53121 Bonn, Germany
[2] Frankfurt Univ Hosp, Ctr Surg, Res Lab, Frankfurt, Germany
[3] Univ Wurzburg, Orthoped Ctr Musculoskeletal Res, D-97070 Wurzburg, Germany
来源：
INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS | 2013年 / 51卷 / 01期
关键词：
CCN/Cyr61; migration; prostate cancer cells (PC-3); integrins; fibronectin; collagen; ECM;
D O I：
10.5414/CPP51047
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
[No abstract available]
引用
收藏
页码：47 / 50
页数：4
相关论文
共 50 条
  • [1] CCN1 (CYR61): Two faces in cancer
    不详
    JOURNAL OF CLINICAL PATHOLOGY, 2005, 58 (05) : 473 - 474
  • [2] The matrix protein CCN1/CYR61 is required for ανβ5-mediated cancer cell migration
    Jandova, Jana
    Beyer, Tracey E.
    Meuillet, Emmanuelle J.
    Watts, George S.
    CELL BIOCHEMISTRY AND FUNCTION, 2012, 30 (08) : 687 - 695
  • [3] The CCN proteins CCN1 (CYR61) and CCN3 (NOV): regulators of trophoblast proliferation and migration
    Kipkeew, F.
    Whitley, G. S.
    Klein, D.
    Winterhager, E.
    Gellhaus, A.
    PLACENTA, 2013, 34 (02) : A85 - A85
  • [4] Hypoxia Modulation of CYR61 (CCN1) and NOV (CCN3) in Trophoblast Cells and Preeclampsia
    Gellhaus, Alexandra
    Wolf, Nadine
    Dunk, Caroline C.
    Schmidt, Markus
    Lyc, Stephen J.
    Winterhager, Elke
    REPRODUCTIVE SCIENCES, 2009, 16 (03) : 171A - 172A
  • [5] Cyr61/CCN1 regulates SHh through Notch signaling in pancreatic cancer cells
    Haque, Inamul
    Majumder, Monami
    Banerjee, Sushanta K.
    Mehta, Smita
    Banerjee, Snigdha
    CANCER RESEARCH, 2012, 72
  • [6] When Breast Cancer Wants to Spread, Suppress CYR61/CCN1
    Hellinger, Johanna
    Silke, Huechel
    Goetz, Lena
    Bauerschmitz, Gerd
    Emons, Guenter
    Gruendker, Carsten
    ONCOLOGY RESEARCH AND TREATMENT, 2020, 43 : 13 - 13
  • [7] Functional domains of CCN1 (Cyr61) regulate breast cancer progression
    O'Kelly, James
    Chung, Alice
    Lemp, Nathan
    Chumakova, Katya
    Yin, Dong
    Wang, He-Jing
    Said, Jonathan
    Gui, Dorina
    Miller, Carl W.
    Karlan, Beth Y.
    Koeffler, H. Phillip
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2008, 33 (01) : 59 - 67
  • [8] CCN1 (CYR61) and CCN3 (NOV) signaling drives human trophoblast cells into senescence and stimulates migration properties
    Kipkeew, Friederike
    Kirsch, Manuela
    Klein, Diana
    Wuelling, Manuela
    Winterhager, Elke
    Gellhaus, Alexandra
    CELL ADHESION & MIGRATION, 2016, 10 (1-2) : 163 - 178
  • [9] Binding of the angiogenic/senescence inducer CCN1/CYR61 to integrin α6β1 drives endocrine resistance in breast cancer cells
    Espinoza, Ingrid
    Yang, Lin
    Vander Steen, Travis
    Vellon, Luciano
    Cuyas, Elisabet
    Verdura, Sara
    Lau, Lester
    Menendez, Javier A.
    Lupu, Ruth
    AGING-US, 2022, 14 (03): : 1200 - 1213
  • [10] Regulation of ccn proteins CYR61 (CCN1) and NOV (CCN3) in human trophoblast cells under hypoxia
    Wolf, Nadine
    Schmidt, Markus
    Dunk, Caroline C.
    Frede, Stilla
    Lye, Stephen J.
    Winterhager, Elke
    Gellhaus, Alexandra
    PLACENTA, 2008, 29 (08) : A89 - A89
12345