Intravenous levetiracetam for treatment of neonatal seizures

被引：34
|
作者：
Rakshasbhuvankar, Abhijeet [1 ,2 ]
Rao, Shripada [1 ,2 ]
Kohan, Rolland [1 ,2 ]
Simmer, Karen [1 ,2 ,3 ]
Nagarajan, Lakshmi [4 ,5 ]
机构：
[1] Princess Margaret Hosp Children, Dept Neonatal Paediat, Perth, WA, Australia
[2] King Edward Mem Hosp Women, Perth, WA, Australia
[3] Univ Western Australia, Sch Womens & Infants Hlth, Perth, WA 6009, Australia
[4] Princess Margaret Hosp Children, Dept Paediat Neurol, Perth, WA 6008, Australia
[5] Univ Western Australia, Sch Paediat & Child Hlth, Perth, WA 6009, Australia
来源：
JOURNAL OF CLINICAL NEUROSCIENCE | 2013年 / 20卷 / 08期
关键词：
Anticonvulsants; Levetiracetam; Newborn; Seizures;
D O I：
10.1016/j.jocn.2012.08.014
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
In this case series we report on eight neonates with refractory seizures who received intravenous levetiracetam when seizures did not respond to two or more conventional anticonvulsants. Six of the eight neonates had an excellent response with either cessation, or reduction in seizures by at least 80%. One neonate showed a partial response while one did not have any reduction in seizure frequency. We did not encounter any adverse effects that could be attributable to levetiracetam. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1165 / 1167
页数：3
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