Community-acquired pneumonia

被引:411
|
作者
Prina, Elena [1 ]
Ranzani, Otavio T. [2 ]
Torres, Antoni [1 ]
机构
[1] Univ Barcelona, Dept Pulmonol, Inst Invest August Pi & Sunyer IDIBAPS, Hosp Clin Barcelona,Ciber Enfermedades Resp CIBER, E-08036 Barcelona, Spain
[2] Univ Sao Paulo, Resp Intens Care Unit, Div Pulm, Heart Inst,Hosp Clin, Sao Paulo, Brazil
来源
LANCET | 2015年 / 386卷 / 9998期
关键词
PNEUMOCOCCAL CONJUGATE VACCINE; BETA-LACTAM MONOTHERAPY; INTENSIVE-CARE-UNIT; C-REACTIVE PROTEIN; ANTIBIOTIC-THERAPY; HOSPITALIZED-PATIENTS; RISK-FACTORS; DOUBLE-BLIND; NONINVASIVE VENTILATION; MYCOPLASMA-PNEUMONIAE;
D O I
10.1016/S0140-6736(15)60733-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Community-acquired pneumonia causes great mortality and morbidity and high costs worldwide. Empirical selection of antibiotic treatment is the cornerstone of management of patients with pneumonia. To reduce the misuse of antibiotics, antibiotic resistance, and side-effects, an empirical, effective, and individualised antibiotic treatment is needed. Follow-up after the start of antibiotic treatment is also important, and management should include early shifts to oral antibiotics, stewardship according to the microbiological results, and short-duration antibiotic treatment that accounts for the clinical stability criteria. New approaches for fast clinical (lung ultrasound) and microbiological (molecular biology) diagnoses are promising. Community-acquired pneumonia is associated with early and late mortality and increased rates of cardiovascular events. Studies are needed that focus on the long-term management of pneumonia.
引用
收藏
页码:1097 / 1108
页数:12
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