Hepatitis-B virus infection predicts mortality of HIV and hepatitis C virus coinfected patients

被引：11

作者：

Teira, Ramon ^{[1
]}

Suarez-Lozano, Ignacio ^{[2
]}

Lozano, Fernando ^{[3
]}

Viciana, Pompeyo ^{[4
]}

Domingo, Pere ^{[5
]}

Galindo, Pepa ^{[6
]}

Geijo, Paloma ^{[7
]}

Terron, Alberto ^{[8
]}

Cosin, Jaime ^{[9
]}

Ribera, Esteban ^{[10
]}

Roca, Bernardino ^{[11
]}

Garcia-Alcalde, Maria L. ^{[12
]}

Sanchez, Trinitario ^{[13
]}

Munoz-Sanz, Agustin ^{[14
]}

Romero, Alberto ^{[15
]}

Lopez-Aldeguer, Jose ^{[16
]}

Pedrol, Enric ^{[17
]}

Vidal, Francesc ^{[18
]}

Garrido, Myriam ^{[19
]}

Munoz, Pepa ^{[20
]}

Puig, Teresa ^{[21
]}

Deig, Elisabeth ^{[22
]}

Estrada, Vicente ^{[23
]}

Castano, Manuel ^{[24
]}

机构：

[1] Hosp Sierrallana, Torrelavega 39300, Spain

[2] Hosp Infanta Elena, Huelva, Spain

[3] Hosp Valme, Seville, Spain

[4] Hosp Virgen Rocio, Seville, Spain

[5] Hosp Santa Creu & Sant Pau, Barcelona, Spain

[6] Hosp Clin, Valencia, Spain

[7] Hosp Virgen Luz, Cuenca, Ecuador

[8] Hosp SAS, Jerez de la Frontera, Spain

[9] Hosp Gen Gregorio Maranon, Madrid, Spain

[10] Hosp Valle De Hebron, Barcelona, Spain

[11] Gen Hosp, Castellon de La Plana, Spain

[12] Hosp Cabuenes, Gijon, Spain

[13] Hosp Virgen Rosell, Cartagena, Spain

[14] Hosp Infanta Cristina, Badajoz, Spain

[15] Hosp Clin, Puerto Real, Spain

[16] Hosp La Fe, E-46009 Valencia, Spain

[17] Hosp Santa Tecla, Tarragona, Spain

[18] IISPV Univ Rovira & Virgili, Hosp Univ Joan XXIII, Tarragona, Spain

[19] VACH Data Management Ctr, Cartaya, Spain

[20] Hosp Basurto, Bilbao, Spain

[21] Hosp Arnau Vilanova, Lleida, Spain

[22] Gen Hosp, Granollers, Spain

[23] Hosp Clin San Carlos, Madrid, Spain

[24] Hosp Carlos Haya, Malaga, Spain

来源：

AIDS | 2013年 / 27卷 / 05期

关键词：

LIVER-DISEASE; VIRAL-HEPATITIS; DUAL INFECTION; HCV; PROGRESSION; PREVALENCE; CLEARANCE; COHORT;

D O I：

10.1097/QAD.0b013e32835ecaf7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To study hepatitis B virus (HBV)-hepatitis C virus (HCV)-HIV triple coinfection in the Spanish VACH cohort, we selected HCV-antibody positive patients who had recorded results for HBV surface antigen (HBsAg) and classified them as HBsAg positive or not. We compared their characteristics and outcome (death by any cause). Six thousand three hundred and seventy-nine patients fulfilled the inclusion criteria. Three hundred and fifty-five (5.6%) were HBsAg positive, which showed an association with mortality (mortality rate ratio: 1.90; 95% confidence interval: 1.42-2.54). This association persisted after adjusting for other prognostic variables.

引用

页码：845 / 848

页数：4

共 50 条

[1] Hepatitis C Virus infection in HIV coinfected patients
Berenguer, J.
[J]. REVISTA CLINICA ESPANOLA, 2010, 210 (07): : 338 - 341
[2] Mortality in siblings of patients coinfected with HIV and hepatitis C virus
Hansen, Ann-Brit Eg
Gerstoft, Jan
Kronborg, Gitte
Pedersen, Court
Sorensen, Henrik Toft
Obel, Niels
[J]. JOURNAL OF INFECTIOUS DISEASES, 2007, 195 (02): : 230 - 235
[3] Treatment of hepatitis B virus infection in patients coinfected with HIV
Benhamou, Y
Bonyhay, L
[J]. GASTROENTEROLOGY CLINICS OF NORTH AMERICA, 2004, 33 (03) : 617 - +
[4] Hepatitis C virus infection is associated with endothelial dysfunction in HIV/hepatitis C virus coinfected patients
Fernandez de Castro, Isabel
Micheloud, Dariela
Berenguer, Juan
Guzman-Fulgencio, Maria
Catalan, Pilar
Miralles, Pilar
Alvarez, Emilio
Carlos Lopez, Juan
Cosin, Jaime
Lorente, Raquel
Angeles Munoz-Fernandez, Ma
Resino, Salvador
[J]. AIDS, 2010, 24 (13) : 2059 - 2067
[5] Reactivation of Hepatitis B Virus Following Treatment of Hepatitis C Virus Infection in Coinfected Patients
Ozaras, Resat
Balkan, Ilker Inanc
Yemisen, Mucahit
Mete, Bilgul
Tabak, Fehmi
[J]. CLINICAL INFECTIOUS DISEASES, 2017, 64 (10) : 1461 - 1462
[6] Reactivation of Hepatitis B Virus Following Treatment of Hepatitis C Virus Infection in Coinfected Patients Reply
Sulkowski, Mark S.
Brainard, Diana M.
Yang, Jenny C.
Gane, Edward J.
[J]. CLINICAL INFECTIOUS DISEASES, 2017, 64 (10) : 1463 - 1463
[7] Telaprevir in patients coinfected with hepatitis C virus and HIV
Gallego Galisteo, M.
Tellez Perez, F.
Infante Chacon, N.
Roldan Morales, J. C.
Perez Perez, M.
Avila Alvarez, J. R.
[J]. INTERNATIONAL JOURNAL OF CLINICAL PHARMACY, 2013, 35 (05) : 972 - 973
[8] Treatment of the hepatitis C virus in patients coinfected with HIV
Khalili, M
Proietti, N
[J]. GASTROENTEROLOGY CLINICS OF NORTH AMERICA, 2004, 33 (03) : 479 - +
[9] ANTIBODY TO HEPATITIS-C VIRUS IN PATIENTS WITH CHRONIC HEPATITIS-B VIRUS-INFECTION
OZYILKAN, E
ARSLAN, M
[J]. JOURNAL OF HEPATOLOGY, 1995, 23 (05): : 630 - 631
[10] THE EFFECT OH HEPATITIS B VIRUS INFECTION ON STEATOSIS IN HEPATITIS C VIRUS COINFECTED PATIENTS: THE BOSTIC STUDY
Goossens, N.
Coppola, N.
Zampino, R.
Stanzione, M.
Wedemeyer, H.
Barrera, F.
Muellhaupt, B.
Moradpour, D.
Semela, D.
Semmo, N.
Malinverni, R.
Heim, M.
George, J.
Manns, M.
Adinolfi, L. E.
Rubbia-Brandt, L.
Negro, F.
[J]. JOURNAL OF HEPATOLOGY, 2014, 60 (01) : S288 - S288

← 1 2 3 4 5 →