Thyroid function testing in neonates born to women with hypothyroidism

被引:8
|
作者
McGovern, Matthew [1 ]
Reyani, Zahra [1 ]
O'Connor, Pamela [1 ]
White, Martin [1 ,2 ]
Miletin, Jan [1 ,3 ,4 ,5 ]
机构
[1] Coombe Women & Infants Univ Hosp, Dublin, Ireland
[2] Royal Coll Surg, Dublin, Ireland
[3] Inst Care Mother & Child, Prague, Czech Republic
[4] UCD Sch Med & Med Sci, Dublin, Ireland
[5] Charles Univ Prague, Sch Med 3, Prague, Czech Republic
关键词
Congenital hypothyroidism; Thyroid function tests; Infant; Newborn; Risk factors; Neonatal screening; CONGENITAL HYPOTHYROIDISM; MANAGEMENT; DIAGNOSIS; NEWBORNS; INFANTS;
D O I
10.1007/s00431-016-2793-8
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Our aim was to assess the utility of serum thyroxine and thyroid stimulating hormone performed at 10-14 days of life in diagnosing congenital hypothyroidism (CH) in babies born to mothers with hypothyroidism. This was a retrospective study of all babies born in a tertiary referral centre for neonatology over a 12-month period. Infants who had thyroid function testing (TFT) checked at 10-14 days of life because of maternal hypothyroidism during the period of study were included. The results of the newborn bloodspot and day 10-14 TFT were recorded along with whether or not patients were subsequently treated. Of the 319 patients included in the study, only two patients were found to have CH and in both cases the newborn blood spot had been abnormal. Conclusion: No extra cases of CH were detected from the thyroid test at 10-14 days and this practice should be discontinued due to the robust nature of existing newborn screening programmes.
引用
收藏
页码:2015 / 2018
页数:4
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