Synthesis of platinum(II) complexes of thymidine and 1-methylthymine (1-MeThy);: crystal structure of cis-[PtCl(1-MeThy)-(PPh3)2]

被引：9
|
作者：
De Napoli, L
Iacovino, R
Messere, A
Montesarchio, D
Piccialli, G
Romanelli, A
Ruffo, F
Saviano, M
机构：
[1] Univ Molise, Fac Sci, I-86170 Isernia, Italy
[2] Univ Naples Federico II, Dipartimento Chim Organ & Biol, I-80134 Naples, Italy
[3] Univ Naples Federico II, CNR, Ctr Biocristallog, I-80134 Naples, Italy
[4] Univ Naples Federico II, Dipartimento Chim, I-80134 Naples, Italy
来源：
JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS | 1999年 / 12期
关键词：
D O I：
10.1039/a901459d
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The reaction of 3',5'-di-O-acetylthymidine with [Pt(PPh3)(4)] and KCl yielded a platinum(II) complex where the platinum is co-ordinated to the nucleobase through the N3 atom. In a similar reaction 1-methylthymine (1-MeThy) furnished the complex cis-[PtCl(1-MeThy)(PPh3)(2)], whose structure was determined by spectroscopic data and single crystal X-ray diffraction. When 1-MeThy was treated with [Pt(PPh3)(4)] in the absence of chloride ions the complex trans-[Pt(OH)(1-MeThy)(PPh3)(2)] was obtained.
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页码：1945 / 1949
页数：5
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