Studies for the synthesis of marine natural products

被引：12

作者：

Williams, David R. ^{[1
]}

Walsh, Martin J. ^{[1
]}

Claeboe, Christopher D. ^{[1
]}

Zorn, Nicolas ^{[1
]}

机构：

[1] Indiana Univ, Dept Chem, Bloomington, IN 47405 USA

来源：

PURE AND APPLIED CHEMISTRY | 2009年 / 81卷 / 02期

关键词：

natural products; xenicanes; peloruside A; asymmetric allylation reactions; B-alkyl Suzuki cross-coupling; Kumada cross-coupling; E-cyclononenes; AGENT PELORUSIDE-A; ALLYLATION; ALDEHYDES; DIASTEREOSELECTIVITY; DITERPENOIDS; PRECATALYST; RING; NHC;

D O I：

10.1351/PAC-CON-08-07-23

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The process of allylic transposition in S-E' reactions is a significant construct for synthesis. The flexibility of a variety of allylation strategies provides for the rational design of pathways to a diverse array of complex targets. Our recent studies of S-E' reactions will examine issues of stereoselectivity and efficiency in the context of applications toward the synthesis of marine natural products such as the xenicane diterpenes, which feature the strained E-cyclononene ring system, and peloruside A, a 16-membered macrocyclic lactone.

引用

页码：181 / 194

页数：14

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