Ceftaroline for meticillin-resistant Staphylococcus aureus bacteraemia: Case series and review of the literature

被引：61
|
作者：
Polenakovik, Hari M. [1 ]
Pleiman, Craig M. [2 ]
机构：
[1] Wright State Univ, Boonshoft Sch Med, Miami Valley Hosp, Dayton, OH 45409 USA
[2] Miami Valley Hosp, Dept Pharm, Dayton, OH USA
来源：
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 2013年 / 42卷 / 05期
关键词：
Ceftaroline; Meticillin-resistant Staphylococcus aureus; MRSA; Bacteraemia; Endocarditis; MINIMUM INHIBITORY CONCENTRATION; METHICILLIN-RESISTANT; DAPTOMYCIN; VANCOMYCIN; ENDOCARDITIS; INFECTIONS; THERAPY;
D O I：
10.1016/j.ijantimicag.2013.07.005
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Data regarding ceftaroline use for meticillin-resistant Staphylococcus aureus bacteraemia (MRSAB) are lacking. Here we review the outcomes of 31 patients with MRSAB treated with ceftaroline, including 9 patients with endocarditis. Clinical success was observed in 23 patients (74.2%). Adverse events associated with prolonged therapy were rare and included eosinophilic pneumonia, rash and diarrhoea. We conclude that ceftaroline can be used for MRSAB. (c) 2013 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.
引用
收藏
页码：450 / 455
页数：6
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