NKTeeing Up B Cell Responses to Viral Infection

被引:3
|
作者
Fontana, Mary F. [1 ]
Pepper, Marion [1 ]
机构
[1] Univ Washington, Sch Med, Dept Immunol, 750 Republican St, Seattle, WA 98109 USA
关键词
COGNATE HELP; NKT CELLS; ACTIVATION; INNATE; MECHANISM; SIGNALS;
D O I
10.1016/j.immuni.2018.02.008
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Activated B cells mature in germinal centers (GCs), but GC initiation during infection is poorly understood. Gaya et al. (2018) show that NKT cells, activated by CD169(+) macrophages, produce an early wave of interleukin-4 (IL-4) that promotes GC formation during viral infection.
引用
收藏
页码:198 / 200
页数:3
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