Synthesis, characterization and biological activity of triorganotin carboxylates containing germanium

被引:0
|
作者
Choudhary, MA [1 ]
Mazhar, M
Salma, SAUNE
Ashraf, S
Malik, A
机构
[1] Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan
[2] Univ Karachi, HEJ Inst Chem, Karachi, Pakistan
来源
TURKISH JOURNAL OF CHEMISTRY | 2002年 / 26卷 / 01期
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中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Some new triorganotin carboxylates containing germanium with general formulae ((RGeCHRCH2COO)-Ge-1-C-2) Sn(CH2C(CH3)(3))(3) where R-1 = N(CH2CH2O)(3) and C6H5, R-2 = C6H5, p-C6H4OCH3 and o- /p-C6H4F were synthesized and characterized by elemental analysis, infrared, multinuclear (H-1, C-13, Sn-119) NMR and mass spectrometry. Antibacterial activity of these compounds was evaluated against the standard drugs ampicilline and amoxicilline, and found to be more active in some cases than the standard drugs.
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页码:125 / 131
页数:7
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