iPSC-based in vitro model of Parkinson's disease caused by OPA1 mutations

被引:0
|
作者
Iannielli, A. [1 ]
Folladori, L. [1 ]
Cancellieri, C. [1 ]
Morabito, G. [1 ]
Massimino, L. [1 ]
Indrigo, M. [1 ]
Segnali, A. [3 ]
Maresca, A. [4 ,5 ]
Caporali, L. [4 ,5 ]
Carelli, V. [4 ,5 ]
Tiranti, V. [3 ]
Broccoli, V. [1 ,2 ]
机构
[1] Ist Sci San Raffaele, Div Neurosci, Stem Cell & Neurogenesis Unit, Milan, Italy
[2] CNR, Natl Res Council, Inst Neurosci, Milan, Italy
[3] IRCCS Fdn Neurol Inst C Besta, Div Mol Neurogenet, Milan, Italy
[4] Bellaria Hosp, IRCCS Inst Neurol Sci Bologna, Bologna, Italy
[5] Univ Bologna, Dept Biomed & Neuromotor Sci, Neurol Unit, Bologna, Italy
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
P097
引用
收藏
页码:A75 / A75
页数:1
相关论文
共 50 条
  • [1] iPSC-based modeling of Parkinson's disease
    Raya, A.
    HUMAN GENE THERAPY, 2016, 27 (11) : A13 - A13
  • [2] An iPSC-Based Platform for Investigating Idiopathic Parkinson's Disease
    Corenblum, M. J.
    Annadurai, A.
    Shrestha, K.
    Madhavan, L.
    CELL TRANSPLANTATION, 2018, 27 (04) : 686 - 687
  • [3] NONSYNDROMIC PARKINSON DISEASE IN A FAMILY WITH AUTOSOMAL DOMINANT OPTIC ATROPHY DUE TO OPA1 MUTATIONS
    Lynch, David S.
    Loh, Samantha H. Y.
    Harley, Jasmine
    Noyce, Alastair J.
    Martins, L. Miguel
    Wood, Nicholas W.
    Houlden, Henry
    Plun-Favreau, Helene
    NEUROLOGY-GENETICS, 2017, 3 (05)
  • [4] Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson's disease
    Kouroupi, Georgia
    Taoufik, Era
    Vlachos, Ioannis S.
    Tsioras, Konstantinos
    Antoniou, Nasia
    Papastefanaki, Florentia
    Chroni-Tzartou, Dafni
    Wrasidlo, Wolfgang
    Bohl, Delphine
    Stellas, Dimitris
    Politis, Panagiotis K.
    Vekrellis, Kostas
    Papadimitriou, Dimitra
    Stefanis, Leonidas
    Bregestovski, Piotr
    Hatzigeorgiou, Artemis G.
    Masliah, Eliezer
    Matsas, Rebecca
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (18) : E3679 - E3688
  • [5] MUTATIONS IN OPA1 EXPAND THE CLINICAL PHENOTYPE OF MITOCHONDRIAL DISEASE
    Chinnery, P.
    Jackson, M.
    Amati-Bonneau, P.
    Yu-Wai-Man, P.
    Gorman, G.
    Duffey, P.
    Baker, M.
    Zeviani, M.
    Horvath, R.
    Miller, J.
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2010, 81 (11): : E32 - E33
  • [6] Advanced human iPSC-based preclinical model for Parkinson's disease with optogenetic alpha-synuclein aggregation
    Kim, Min Seong
    Ra, Eun A.
    Kweon, Sin Ho
    Seo, Bo Am
    Ko, Han Seok
    Oh, Yohan
    Lee, Gabsang
    CELL STEM CELL, 2023, 30 (07) : 973 - +
  • [7] iPSC-based drug screening for Huntington's disease
    Zhang, Ningzhe
    Bailus, Barbara J.
    Ring, Karen L.
    Ellerby, Lisa M.
    BRAIN RESEARCH, 2016, 1638 : 42 - 56
  • [8] Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease
    Sommer, Annika
    Maxreiter, Franz
    Krach, Florian
    Fadler, Tanja
    Grosch, Janina
    Maroni, Michele
    Graef, Daniela
    Eberhardt, Esther
    Riemenschneider, Markus J.
    Yeo, Gene W.
    Kohl, Zacharias
    Xiang, Wei
    Gage, Fred H.
    Winkler, Juergen
    Prots, Iryna
    Winner, Beate
    CELL STEM CELL, 2018, 23 (01) : 123 - +
  • [9] Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson's disease
    Brazdis, Razvan-Marius
    Alecu, Julian E.
    Marsch, Daniel
    Dahms, Annika
    Simmnacher, Katrin
    Loerentz, Sandra
    Brendler, Anna
    Schneider, Yanni
    Marxreiter, Franz
    Roybon, Laurent
    Winner, Beate
    Xiang, Wei
    Prots, Iryna
    HUMAN MOLECULAR GENETICS, 2020, 29 (07) : 1180 - 1191
  • [10] Multi-system neurological disease is common in patients with OPA1 mutations
    Yu-Wai-Man, P.
    Griffiths, P. G.
    Gorman, G. S.
    Lourenco, C. M.
    Wright, A. F.
    Auer-Grumbach, M.
    Toscano, A.
    Musumeci, O.
    Valentino, M. L.
    Caporali, L.
    Lamperti, C.
    Tallaksen, C. M.
    Duffey, P.
    Miller, J.
    Whittaker, R. G.
    Baker, M. R.
    Jackson, M. J.
    Clarke, M. P.
    Dhillon, B.
    Czermin, B.
    Stewart, J. D.
    Hudson, G.
    Reynier, P.
    Bonneau, D.
    Marques, W., Jr.
    Lenaers, G.
    McFarland, R.
    Taylor, R. W.
    Turnbull, D. M.
    Votruba, M.
    Zeviani, M.
    Carelli, V.
    Bindoff, L. A.
    Horvath, R.
    Amati-Bonneau, P.
    Chinnery, P. F.
    BRAIN, 2010, 133 : 771 - 786