Siderophore production by Staphylococcus aureus and identification of iron-regulated proteins

被引:72
|
作者
Courcol, RJ
Trivier, D
Bissinger, MC
Martin, GR
Brown, MRW
机构
[1] HOP A CALMETTE,BACTERIOL LAB,F-59037 LILLE,FRANCE
[2] ASTON UNIV,DEPT PHARMACEUT & BIOL SCI,MICROBIOL RES GRP,BIRMINGHAM B4 7ET,W MIDLANDS,ENGLAND
关键词
D O I
10.1128/IAI.65.5.1944-1948.1997
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Siderophore activity of Staphylococcus aureus was detected in an iron-restricted chemically defined medium, The molecular mass of this siderophore, called aureochelin, was 577 Da. Surface-associated proteins of 120, 88, 57, 35, and 33 kDa were mainly expressed under iron restriction conditions, Results showed a relationship between siderophore production and the existence of the 120- and 88-kDa proteins, Western blotting of surface-associated proteins revealed that these proteins were recognized both by patients sera and polyclonal rabbit serum.
引用
收藏
页码:1944 / 1948
页数:5
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