DERMATOSIS BY LINEAL IGA IN INFANCY: IN REGARDS TO A CASE. HOSPITAL UNIVERSITARIO DR. ANGEL LARRALDE

It is a rare, infrequent disease that manifests itself by tense bullous vesicle-like lesions, usually grouped in clusters that give the appearance of a pearl necklace. It is of autoimmune etiology, characterized by linear band IgA deposits in the dermal-epidermal basement membrane, which are observed with the direct immunofluorescence technique. Depending on the age of onset, the following are distinguished: the infantile form, which begins before the age of 5 and affects both sexes equally. The differential diagnosis must be established mainly with other self-immune dermatoses, such as dermatitis herpetiformis and bullous pemphigoid. The first-line treatment is dapsone, with an excellent short-term response. The disease is benign and tends to progress in outbreaks until its spontaneous resolution. We present the case of a 6-month-old male infant whose mother reports the onset of the current disease 2 weeks prior to admission when he begins to present erythematous, papular lesions in the anterior chest, right axillary region and dorsal region of the lower limbs. The mother applies a Gliricidia sepium plant known as "mouse plant ", thus exacerbating lesions, which is why antimicrobial coverage with clindamycin is indicated for coverage of Gram+ Gram-and anaerobic germs. In addition, corticosteroids such as methylprenisolone were indicated, obtaining improvement of the symptoms in the following 14 days when he is discharged with outpatient treatment.