Assessing the in vitro anti-HBV activity of combinations including CRV431, TXL, and prototype capsid assembly modulators

被引：0
|
作者：
Foster, R. [1 ]
Greytok, J. [1 ]
Ure, D. [1 ]
Trepanier, D. [1 ]
Kulp, J. [2 ]
Gallay, P. [3 ]
机构：
[1] ContraVir Pharmaceut Inc, Res & Dev, Edmonton, AB, Canada
[2] Barach S Blumberg Inst, Res, Doylestown, PA USA
[3] Scripps Res Inst, Dept Immunol & Microbial Sci, San Diego, CA USA
来源：
JOURNAL OF HEPATOLOGY | 2018年 / 68卷
关键词：
D O I：
10.1016/S0168-8278(18)31801-4
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
SAT-356
引用
收藏
页码：S768 / S768
页数：1
相关论文
共 8 条
  • [1] Independent and Combinational Anti-HBV Effects of CRV431 and TXL in the HBV Transgenic Mouse Model
    Foster, Robert T.
    Ure, Daren R.
    Trepanier, Daniel J.
    Greytok, Jill
    Sullivan-Bolyai, John Z.
    Gallay, Philippe
    [J]. HEPATOLOGY, 2017, 66 : 484A - 484A
  • [2] HBV peptide array demonstrates candidate mechanisms of CRV431 anti-HBV activity
    Foster, R.
    Levin, A.
    Le, C.
    Ure, D.
    Trepanier, D.
    Tyrrell, L.
    [J]. JOURNAL OF HEPATOLOGY, 2018, 68 : S767 - S768
  • [3] Design, synthesis and anti-HBV activity study of novel HBV capsid assembly modulators
    Liang, Minghui
    Liu, Linyue
    Liu, Jun
    Yang, Zechun
    Wang, Mei
    Xie, Yong
    Cai, Yuqing
    Xue, Peng
    Chen, Yunfu
    Zhan, Peng
    Jia, Haiyong
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 112
  • [4] CRV431 and CMX157: anti-HBV combination effects in vitro between a cyclophilin inhibitor and a nucleotide prodrug
    Foster, R. T.
    Trepanier, D. J.
    Ure, D. R.
    Greytok, J.
    Kulp, J. L.
    Gallay, P.
    [J]. JOURNAL OF HEPATOLOGY, 2017, 66 (01) : S699 - S699
  • [5] Anti-HBV activity of in vitro combinations of tenofovir with nucleoside analogs
    Zhu, Yuao
    Qi, Xiaoping
    Delaney, William E.
    Curtis, Maria
    Miller, Michael D.
    Borroto-Esoda, Katyna
    [J]. HEPATOLOGY, 2006, 44 (04) : 253A - 253A
  • [6] Discovery of Novel Pyrimidine-Based Capsid Assembly Modulators as Potent Anti-HBV Agents
    Kim, WooChan
    Kang, Jung-Ah
    Park, Minji
    Jeong, Pyeong-Hwa
    Kim, Yoon Jun
    Cho, Yuri
    Park, Sung-Gyoo
    Kim, Yong-Chul
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (09) : 5500 - 5518
  • [7] In vitro anti-HBV activity of telbivudine/tenofovir and telbivudine/entecavir combinations
    Patty, April
    Li, Bin
    Serra, Ilaria
    Standring, David N.
    Seifer, Maria
    [J]. HEPATOLOGY, 2007, 46 (04) : 663A - 663A
  • [8] Anti-HBV activity of the HBV capsid assembly modulator JNJ-56136379 across full-length genotype A-H clinical isolates and core site-directed mutants in vitro
    Verbinnen, Thierry
    Tan, Ying
    Wang, Gengyan
    Dehertogh, Pascale
    Vergauwen, Karen
    Neefs, Jean-Marc
    Jacoby, Edgar
    Lenz, Oliver
    Berke, Jan Martin
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2020, 75 (09) : 2526 - 2534
1