NT-proBNP and Cardiovascular Dysfunction in Chronic Liver Disease

被引：0

作者：

Cozma, Lucia Corina Dima ^{[1
]}

Ghiciuc, Cristina Mihaela ^{[2
]}

Mitu, Florin ^{[1
]}

Dascalu, Cristina Gena ^{[3
]}

机构：

[1] Grigore T Popa Univ Med & Pharm, Fac Med, Med Dept 1, 16 Univ Str, Iasi 700115, Romania

[2] Grigore T Popa Univ Med & Pharm, Fac Med, Dept Pharmacol, 16 Univ Str, Iasi 700115, Romania

[3] Grigore T Popa Univ Med & Pharm, Fac Dent Med, Dept Med Informat & Biostat, 16 Univ Str, Iasi 700115, Romania

来源：

REVISTA DE CHIMIE | 2018年 / 69卷 / 02期

关键词：

NT-proBNP; cardiovascular dysfunction; liver cirrhosis; chronic hepatitis; NATRIURETIC PEPTIDE;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Plasma NT-proBNP levels are elevated in heart disease, especially in the presence of ascites-edema syndrome and left ventricular overload. Previous studies have reported cardiovascular dysfunction correlated with the severity of liver damage. This prospective study enrolled 65 subjects with the diagnosis of liver cirrhosis, 82 with chronic hepatitis and 65 healthy subjects in the control group. In chronic hepatitis, NT-proBNP has been shown to be an early marker of diastolic dysfunction and left ventricular remodeling, while in liver cirrhosis it also correlated with portopulmonary hypertension.

引用

页码：525 / 528

页数：4

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