Synthesis of novel pyrano fused quinolones, coumarins, and pyridones

被引:17
|
作者
Toche, RB
Jachak, MN
Sabnis, RW
Kappe, T [3 ]
机构
[1] KTHM Coll, Dept Chem, Nashik 422002, India
[2] Brewer Sci Inc, Rolla, MO 65401 USA
[3] Graz Univ, Inst Organ Chem, A-8010 Graz, Austria
关键词
D O I
10.1002/jhet.5570360222
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel efficient synthesis of pyrano fused heterocycles namely, pyrano[3,2-c]quinoline-2,5(6H)-diones 3a-e, 7b-d, pyrano[3,2-c]benzopyran-2,5(6H)-dione (7f), and pyrano[3,2-c]pyridine-2,5(6H)-diones 10, 11 was achieved by the condensation of 4-hydroxy-2-(1H)-quinolones 1a-e, 4-hydroxycoumarin (1f), or 4-hydroxy-2(1H)-pyridone (9) with alpha-acetyl-gamma-butyrolactone (2) or the sodium salt of alpha-formyl-gamma-butyrol actone (6), respectively, in the presence of ammonium acetate.
引用
收藏
页码:467 / 471
页数:5
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