Position Statement: A Pragmatic Approach for Medical Cannabis and Patients with Rheumatic Diseases

被引:37
|
作者
Fitzcharles, Mary-Ann [1 ,2 ,3 ,4 ,5 ]
Niaki, Omid Zahedi [1 ,2 ,3 ,4 ,5 ]
Hauser, Winfried [1 ,2 ,3 ,4 ,5 ]
Hazlewood, Glen [1 ,2 ,3 ,4 ,5 ]
Blocka, Kenneth
Bombardier, Claire
Bernatsky, Sasha
Gong, Jeff
Huber, Adam
Jung, Michelle
Pope, Janet
Scuccimarri, Rosie
Thorne, J. Carter
Tugwell, Peter
Wodkowski, Michael
机构
[1] McGill Univ, Alan Edwards Pain Management Unit, Hlth Ctr, Montreal, PQ, Canada
[2] McGill Univ, Hlth Ctr, Div Rheumatol, Montreal, PQ, Canada
[3] Univ Alberta, Div Rheumatol, Calgary, AB, Canada
[4] Klinikum Saarbrucken, Dept Internal Med 1, Saarbrucken, Germany
[5] Tech Univ Munich, Dept Psychosomat Med & Psychotherapy, Munich, Germany
关键词
RHEUMATIC DISEASE; MEDICAL CANNABIS; MARIJUANA USE; PAIN; SAFETY; TOLERABILITY; ARTHRITIS; EFFICACY; ALLERGY; POTENCY;
D O I
10.3899/jrheum.181120
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective. Pain is one reason some rheumatology patients may consider use of medical cannabis, a product increasingly perceived as a safe and neglected natural treatment option for many conditions. Legalization of recreational cannabis in Canada will promote access to cannabis. Physicians must therefore provide patients with the best evidence-based information regarding the medicinal effects and harm of cannabis. Methods. The Canadian Rheumatology Association (CRA) mandated the development of a position statement for medical cannabis and the rheumatology patient. The current literature regarding the effects of medical cannabis for rheumatology patients was assessed, and a pragmatic position statement to facilitate patient care was developed by the Therapeutics Committee of the CRA and approved by the CRA board. Results. There are no clinical trials of medical cannabis in rheumatology patients. Evidence is insufficient about the benefit of pharmaceutical cannabinoids in fibromyalgia, osteoarthritis, rheumatoid arthritis, and back pain, but there is evidence of a high risk of harm. Extrapolating from other conditions, medical cannabis may provide some symptom relief for some patients. Short-term risks of psychomotor effects can be anticipated, but longterm risks have not been determined and are of concern. Conclusion. Despite lack of evidence for use of medical cannabis in rheumatology patients, we acknowledge the need to provide empathetic and pragmatic guidance for patient care. This position statement aims to facilitate the dialogue between patients and healthcare professionals in a mutually respectful manner to ensure harm reduction for patients and society.
引用
收藏
页码:532 / 538
页数:7
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