Use of anakinra in severe COVID-19: A case report

被引：55
|
作者：
Filocamo, Giovanni [1 ]
Mangioni, Davide [1 ,2 ,3 ]
Tagliabue, Paola [1 ,4 ]
Aliberti, Stefano [1 ,2 ,5 ,6 ]
Costantino, Giorgio [1 ,2 ,7 ]
Minoia, Francesca [1 ,8 ]
Bandera, Alessandra [1 ,2 ,3 ]
机构：
[1] Osped Maggiore Policlin, Fdn IRCCS Ca Granda, Milan, Italy
[2] Univ Milan, Milan, Italy
[3] Univ Milan, Fdn IRCCS Ca Granda Osped Maggiore Policlin, Dept Internal Med, Infect Dis Unit,Dept Pathophysiol & Transplantat, Via Francesco Sforza 35, I-20122 Milan, Italy
[4] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Anesthesia Reanimat & Urgent Emergency Care, Via Francesco Sforza 35, I-20122 Milan, Italy
[5] Univ Milan, Internal Med Dept, Dept Pathophysiol & Transplantat, Resp Unit, Via Francesco Sforza 35, I-20122 Milan, Italy
[6] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Cyst Fibrosis Adult Ctr, Via Francesco Sforza 35, I-20122 Milan, Italy
[7] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Unita Operat Complessa Pronto Soccorso & Med Urge, Via Francesco Sforza 35, I-20122 Milan, Italy
[8] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Pediat Medium Intens Care Unit, Pediat Rheumatol, Clin Marchi, Via Commenda 9, I-20123 Milan, Italy
来源：
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES | 2020年 / 96卷
关键词：
Anakinra; IL-1; COVID-19; Treatment; Biologic;
D O I：
10.1016/j.ijid.2020.05.026
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Coronavirus disease 19 is a global healthcare emergency with a high lethality rate. Relevant inflammatory cytokine storm is associated with severity of disease, and IL-1 inhibition is a cornerstone treatment for hyperinflammatory diseases. We present here the case of a patient with critical COVID-19 successfully treated with IL-1 receptor antagonist (anakinra). (C) 2020 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
引用
收藏
页码：607 / 609
页数：3
相关论文
共 50 条
  • [1] Use of Anakinra to Prevent Mechanical Ventilation in Severe COVID-19: A Case Series
    Navarro-Millan, Iris
    Sattui, Sebastian E.
    Lakhanpal, Amit
    Zisa, Diane
    Siegel, Caroline H.
    Crow, Mary K.
    [J]. ARTHRITIS & RHEUMATOLOGY, 2020, 72 (12) : 1990 - 1997
  • [2] Anakinra for severe forms of COVID-19
    Laine, Marc
    Bonello, Laurent
    [J]. LANCET RHEUMATOLOGY, 2020, 2 (10): : E586 - E586
  • [3] Case Report: Use of Anakinra in Multisystem Inflammatory Syndrome During COVID-19 Pandemic
    Della Paolera, Sara
    Valencic, Erica
    Piscianz, Elisa
    Moressa, Valentina
    Tommasini, Alberto
    Sagredini, Raffaella
    Kiren, Valentina
    Comar, Manola
    Taddio, Andrea
    [J]. FRONTIERS IN PEDIATRICS, 2021, 8
  • [4] Anakinra for severe forms of COVID-19 Reply
    Hayem, Gilles
    Huet, Thomas
    Jouveshomme, Stephane
    Beaussier, Helene
    Chatellier, Gilles
    Mourad, Jean-Jacques
    [J]. LANCET RHEUMATOLOGY, 2020, 2 (10): : E587 - E588
  • [5] Interleukin-1 receptor antagonist anakinra in association with remdesivir in severe COVID-19: A case report
    Franzetti, Marco
    Pozzetti, Ugo
    Carugati, Manuela
    Pandolfo, Alessandro
    Molteni, Chiara
    Faccioli, Paolo
    Castaldo, Gioacchino
    Longoni, Ernesto
    Ormas, Valentina
    Iemoli, Enrico
    Piconi, Stefania
    [J]. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2020, 97 : 215 - 218
  • [6] Anakinra for severe forms of COVID-19: a cohort study
    Huet, Thomas
    Beaussier, Helene
    Voisin, Olivier
    Jouveshomme, Stephane
    Dauriat, Gaelle
    Lazareth, Isabelle
    Sacco, Emmanuelle
    Naccache, Jean-Marc
    Bezie, Yvonnick
    Laplanche, Sophie
    Le Berre, Alice
    Le Pavec, Jerome
    Salmeron, Sergio
    Emmerich, Joseph
    Mourad, Jean-Jacques
    Chatellier, Gilles
    Hayem, Gilles
    [J]. LANCET RHEUMATOLOGY, 2020, 2 (07): : E393 - E400
  • [7] Current evidence on the use of anakinra in COVID-19
    Khani, Elnaz
    Shahrabi, Marzieh
    Rezaei, Haleh
    Pourkarim, Fariba
    Afsharirad, Hoda
    Solduzian, Mohammad
    [J]. INTERNATIONAL IMMUNOPHARMACOLOGY, 2022, 111
  • [8] Successful Treatment of Severe COVID-19 Pneumonia with Simultaneous Tocilizumab and Anakinra - A Case Series
    Haibel, Hildrun
    Angermair, Stefan
    Schumann, Michael
    Vahldiek, Janis
    Poddubnyy, Denis
    Schneider, Thomas
    [J]. ARTHRITIS & RHEUMATOLOGY, 2021, 73 : 392 - 393
  • [9] Targeting the inflammatory cascade with anakinra in moderate to severe COVID-19 pneumonia: case series
    Aouba, Achille
    Baldolli, Aurelie
    Geffray, Loik
    Verdon, Renaud
    Bergot, Emmanuel
    Martin-Silva, Nicolas
    Justet, Aurelien
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2020, 79 (10) : 1381 - 1381
  • [10] A meta analysis on the utility of Anakinra in severe COVID-19 disease
    Hussein, Aliae A. R. Mohamed
    Sayad, Reem
    Abdelshafi, Abdelrahman
    Hammam, Islam Abdelaal
    Kedwany, Ahmed M.
    Elkholy, Shrouk Alaa-eldein
    Ibrahim, Islam H.
    [J]. CYTOKINE, 2023, 169
12345