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Coordinate expression of β1 integrins and their regulator, TGF β2 at the floor plate of the medulla oblongata is correlated with the crossing of the fibers of olivocerebellar projection in mice
被引：1
|作者：
Ohyama, K
Kawamura, K
机构：
[1] Univ Sheffield, Ctr Dev Genet, Sheffield S10 2TN, S Yorkshire, England
[2] Keio Univ, Sch Med, Dept Anat, Shinjuku Ku, Tokyo 1608582, Japan
来源：
关键词：
TGF beta 2;
beta;
1;
integrin;
olivocerebellar projection;
midline;
floor plate;
D O I：
10.1016/S0165-3806(01)00329-7
中图分类号：
Q [生物科学];
学科分类号：
07 ;
0710 ;
09 ;
摘要：
During embryonic day 11 (E11) to E16, contact-dependent interacting Molecules beta1 integrins and their putative regulator TGF beta2 are coordinately expressed at the floor plate in the caudal part of mouse myelencephalon. Their expression disappears at E18. Consistent with the peak of their expression (E13-E16). olivocerebellar fibers primarily cross the floor plate. These data indicate that spatiotemporal expression of beta1 integrins and TGF beta2 is correlated with the crossing of olivocerebellar fibers. (C) 2002 Elsevier Science BY. All rights reserved.
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页码：77 / 80
页数：4
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