Role of emotional stress in the pathophysiology of Graves' disease

被引:36
|
作者
Falgarone, Geraldine [1 ,2 ]
Heshmati, Hassan M. [3 ]
Cohen, Regis [4 ]
Reach, Gerard [4 ]
机构
[1] Hop Univ Paris Seine St Denis, Avicenne Hosp, AP HP, Serv Rhumatol, F-93009 Bobigny, France
[2] Univ Paris 13, EA 4222, Li2P, F-93009 Bobigny, France
[3] Gelesis Inc, Anthem, AZ 85086 USA
[4] Hop Univ Paris Seine St Denis, Avicenne Hosp, AP HP, Serv Endocrinol Diabetol & Malad Metab, F-93009 Bobigny, France
关键词
AUTOIMMUNE THYROID-DISEASE; REGULATORY T-CELLS; IMMUNE RECONSTITUTION SYNDROME; LIFE EVENTS; INFLAMMATORY CYTOKINES; HASHIMOTO THYROIDITIS; HYPERTHYROIDISM; PREGNANCY; PATHOGENESIS; EXPRESSION;
D O I
10.1530/EJE-12-0539
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The role of stress in the pathophysiology of Graves' disease is suggested by several clinical observations, by recent advances in immunology and by better understanding of autoimmune diseases which provides new insights into potential effects of stress hormones on T helper cell imbalance involved in the pathogenesis of autoimmune diseases. Stress management should therefore be an important part of the treatment of Graves' disease, as stress reduction may improve the effect of therapy. However, this field still requires interventional data to support stress management in the treatment of Graves' disease. European Journal of Endocrinology 168 R13-R18
引用
收藏
页码:R13 / R18
页数:6
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