In vivo THz sensing of the cornea of the eye

被引：39
|
作者：
Ozheredov, Ilya [1 ,2 ,5 ]
Prokopchuk, Mikhail [1 ,2 ]
Mischenko, Mikhail [1 ,2 ]
Safonova, Tatiana [3 ]
Solyankin, Petr [1 ,2 ,4 ,5 ]
Larichev, Andrey [1 ,2 ]
Angeluts, Andrey [1 ,2 ]
Balakin, Alexei [1 ,2 ,4 ,5 ]
Shkurinov, Alexander [1 ,2 ,4 ,5 ]
机构：
[1] Lomonosov Moscow State Univ, Fac Phys, Moscow, Russia
[2] Lomonosov Moscow State Univ, Int Laser Ctr, Moscow, Russia
[3] Res Inst Eye Dis, Moscow, Russia
[4] Russian Acad Sci, Inst Laser & Informat Technol Branch, Fed Sci Res Ctr Crystallog & Photon, Shatura, Russia
[5] Univ Shanghai Sci & Technol, Terahertz Technol Innovat Res Inst, Shanghai Key Lab Modern Opt Syst, Terahertz Spectrum & Imaging Technol Cooperat Inn, Shanghai, Peoples R China
来源：
LASER PHYSICS LETTERS | 2018年 / 15卷 / 05期
关键词：
terahertz technology; eye; corneal tissue; tear film; COLLAGEN FIBRILS; FILM; DYNAMICS;
D O I：
10.1088/1612-202X/aaac76
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
Measurement of the absolute value of the humidity of the cornea of the human eye and its dynamics is of paramount importance for the preservation of eyesight. In the present paper we have demonstrated that terahertz technologies can be practically applied for quantitative measurement of the physiological dynamics of tear film and sensing of corneal tissue hydration. We suggest uses of the equipment for application in clinics and a method for absolute calibration of the values for measurement. The proposed method is fundamentally different from existing and currently available methods of ophthalmological diagnosis. This suggests that the developed technique may have high diagnostic significance and can be used in the study and treatment of several diseases of the ocular surface.
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页数：8
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