Calcium and Heme Induce Distinct Conformational States of the Human BK (Slo1) Channel Gating Ring

被引：1
|
作者：
Yusifov, Taleh [1 ]
Javaherian, Anoosh D. [1 ]
Heinemann, Stefan H. [2 ]
Hoshi, Toshinori [3 ]
Olcese, Riccardo [1 ,4 ]
机构：
[1] Univ Calif Los Angeles, David Geffen Sch Med, Dept Anesthesiol, Div Mol Med, Los Angeles, CA 90095 USA
[2] Univ Jena, Dept Biophys, Jena, Germany
[3] Univ Penn, Dept Physiol, Philadelphia, PA 19104 USA
[4] Univ Calif Los Angeles, David Geffen Sch Med, Cardiovasc Res Lab CVRL, Los Angeles, CA 90095 USA
来源：
BIOPHYSICAL JOURNAL | 2012年 / 102卷 / 03期
关键词：
D O I：
10.1016/j.bpj.2011.11.3737
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
引用
收藏
页码：687A / 688A
页数：2
相关论文
共 50 条
  • [1] Heme-Driven Conformational Changes in the Human Slo1 BKCa Channel Gating Ring
    Yusifov, Taleh
    Javaherian, Anoosh
    Gandhi, Chris
    Hou, Shangwei
    Heinemann, Stefan H.
    Hoshi, Toshinori
    Olcese, Riccardo
    BIOPHYSICAL JOURNAL, 2010, 98 (03) : 126A - 126A
  • [2] Evidence for Lipid-Induced Structural Rearrangements in the Human BK (Slo1) Channel Gating Ring
    Yusifov, Taleh
    Javaherian, Anoosh D.
    Heinemann, Stefan H.
    Hoshi, Toshinori
    Olcese, Riccardo
    BIOPHYSICAL JOURNAL, 2012, 102 (03) : 688A - 688A
  • [3] Membrane lipids in allosteric gating of the Slo1 BK channel
    Hoshi, Toshinori
    Heinemann, Stefan H.
    Tian, Yutao
    BIOPHYSICAL JOURNAL, 2024, 123 (03) : 256A - 256A
  • [4] Structural Studies of the Apo and Ca2+-Bound States of the Human BK (SLO1) Channel Gating Ring in Solution
    Yusifov, Taleh
    Gandhi, Chris S.
    Pantazis, Antonios
    Olcese, Riccardo
    BIOPHYSICAL JOURNAL, 2013, 104 (02) : 473A - 473A
  • [5] Heme regulates allosteric activation of the Slo1 BK channel
    Horrigan, FT
    Heinemann, SH
    Hoshi, T
    JOURNAL OF GENERAL PHYSIOLOGY, 2005, 126 (01): : 7 - 21
  • [6] Brief structural insight into the allosteric gating mechanism of BK (Slo1) channel
    Almassy, Janos
    Nanasi, Peter P.
    CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2019, 97 (06) : 498 - 502
  • [7] The Mechanics of Voltage Sensing in the Human BK Channel (Slo1)
    Pantazis, Antonios
    Olcese, Riccardo
    BIOPHYSICAL JOURNAL, 2012, 102 (03) : 688A - 688A
  • [8] The mechanism of the heme action on Slo1 BK channels
    Hoshi, T
    Horrigan, FT
    Heinemann, SH
    BIOPHYSICAL JOURNAL, 2005, 88 (01) : 102A - 102A
  • [9] Baseline Properties of Slo1 K+ (BK) Channels Without the Gating Ring
    Geng, Yanyan
    Budelli, Gonzalo
    Butler, Alice
    Santi, Celia
    Ferreira, Juan
    Salkoff, Lawrence
    Magleby, Karl L.
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 436A - 436A
  • [10] On the Properties of the RCK1 Domain of the Human BK (SLO1) Channel
    Yusifov, Taleh
    Javaherian, Anoosh
    Pantazis, Antonios
    Gandhi, Chris
    Olcese, Riccardo
    BIOPHYSICAL JOURNAL, 2011, 100 (03) : 581 - 581
12345