Host-pathogen systems biology

被引：49
|
作者：
Forst, CV [1 ]
机构：
[1] Los Alamos Natl Lab, Biosci Div, Los Alamos, NM 87545 USA
来源：
DRUG DISCOVERY TODAY | 2006年 / 11卷 / 5-6期
关键词：
D O I：
10.1016/S1359-6446(05)03735-9
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Unlike traditional biological research that focuses on a small set of components, systems biology studies the complex interactions between a large number of genes, proteins and other elements of biological networks and systems. Host-pathogen systems biology examines the interactions between the components of two distinct organisms, either a microbial or viral pathogen and its animal host or two different microbial species in a community. With the availability of complete genomic sequences of various hosts and pathogens, together with breakthroughs in proteomics, metabolomics and other experimental areas, the investigation of host-pathogen systems on a multitude of levels of detail has come within reach.
引用
收藏
页码：220 / 227
页数：8
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