Multicenter, Randomized Crossover Trial Comparing Recombinant Von Willebrand Factor and Tranexamic Acid for Heavy Menstrual Bleeding in Von Willebrand Disease

被引：0

作者：

Ragni, Margaret, V ^{[1
,2
]}

Rothenberger, Scott ^{[3
]}

Feldman, Robert ^{[3
]}

Nance, Danielle ^{[4
]}

Leavitt, Andrew D. ^{[5
]}

Malec, Lynn ^{[6
]}

Sidonio, Robert F., Jr. ^{[7
,8
]}

Kraut, Eric H. ^{[9
]}

Lasky, Joseph L., III ^{[10
]}

Philipp, Claire S. ^{[11
]}

Angelini, Dana E. ^{[12
]}

Pruthi, Rajiv K. ^{[13
]}

Hwang, Nina ^{[14
]}

Wheeler, Allison P. ^{[15
]}

Kulkarni, Roshni ^{[16
]}

Seaman, Craig D. ^{[17
,18
]}

Xavier, Frederico ^{[2
,19
]}

Machin, Nicoletta C. ^{[1
,2
]}

Meyer, Michael ^{[20
]}

Bellissimo, Daniel ^{[21
]}

Smith, Kenneth J. ^{[22
]}

Merricks, Elizabeth P. ^{[23
,24
]}

Nichols, Timothy C. ^{[23
,24
]}

Ivanco, Dana ^{[25
]}

Vehec, Deborah ^{[25
]}

Koerbel, Glory ^{[3
]}

Althouse, Andrew D. ^{[3
]}

机构：

[1] Univ Pittsburgh, Pittsburgh, PA USA

[2] Hemophilia Ctr Western Penn, Pittsburgh, PA USA

[3] Univ Pittsburgh, Ctr Res Hlth Care Data Ctr, Pittsburgh, PA USA

[4] Banner MD Anderson Canc Ctr, Gilbert, AZ USA

[5] Univ Calif San Francisco, Dept Lab Med, San Francisco, CA USA

[6] Versiti, Blood Res Inst, Milwaukee, WI USA

[7] Emory Univ, Aflac Canc & Blood Disorders, Atlanta, GA 30322 USA

[8] Emory Univ, Aflac Canc & Blood Disorders Ctr, Decatur, GA 30322 USA

[9] Ohio State Univ, Div Hematol, Columbus, OH USA

[10] Cure 4 Kids Fdn, Las Vegas, NV USA

[11] Rutgers State Univ, Med, New Brunswick, NJ USA

[12] Cleveland Clin Fdn, Taussig Canc Inst, Dept Hematol & Med Oncol, Avon Lake, OH USA

[13] Mayo Clin, Div Hematol, Rochester, MN USA

[14] CHOC Childrens Hosp, Ctr Inherited Blood Disorders CIBD, Orange, CA USA

[15] Vanderbilt Univ, Med Ctr, Nashville, TN USA

[16] Michigan State Univ, Ctr Bleeding & Clotting Disorders, E Lansing, MI 48824 USA

[17] Univ Pittsburgh, Warrendale, PA USA

[18] Hemophilia Ctr Western Penn, Warrendale, PA USA

[19] Univ Pittsburgh, Childrens Hosp Pittsburgh, Pittsburgh, PA 15213 USA

[20] Vitalant Coagulat Lab, Pittsburgh, PA USA

[21] Univ Pittsburgh, Clin Genom Lab, Pittsburgh, PA USA

[22] Univ Pittsburgh, Sch Med, Pittsburgh, PA USA

[23] Univ N Carolina, Dept Pathol & Lab Med, Chapel Hill, NC USA

[24] Univ N Carolina, UNC Blood Res Ctr, Chapel Hill, NC 27515 USA

[25] Hemophilia Ctr Western, Pittsburgh, PA USA

来源：

BLOOD | 2022年 / 140卷

关键词：

D O I：

10.1182/blood-2022-156921

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1413 / 1415

页数：3

共 50 条

[1] Recombinant von Willebrand factor and tranexamic acid for heavy menstrual bleeding in patients with mild and moderate von Willebrand disease in the USA (VWDMin): a phase 3, open-label, randomised, crossover trial
Ragni, Margaret, V
Rothenberger, Scott
Feldman, Robert
Nance, Danielle
Leavitt, Andrew
Malec, Lynn
Kulkarni, Roshni
Sidonio Jr, Robert
Kraut, Eric
Lasky, Joseph
Pruthi, Rajiv
Angelini, Dana
Philipp, Claire
Hwang, Nina
Wheeler, Allison P.
Seaman, Craig
Machin, Nicoletta
Xavier, Frederico
Meyer, Michael
Bellissimo, Daniel
Humphreys, Gregory
Smith, Kenneth J.
Merricks, Elizabeth P.
Nichols, Timothy C.
Ivanco, Dana
Vehec, Deborah
Koerbel, Glory
Althouse, Andrew D.
[J]. LANCET HAEMATOLOGY, 2023, 10 (08): : E612 - E623
[2] Elevated von Willebrand factor levels during heavy menstrual bleeding episodes limit the diagnostic utility for von Willebrand disease
Brown, Megan C.
White, Michael H.
Friedberg, Rachel
Woods, Kalinda
Childress, Krista
Kulkarni, Mona
Sidonio, Robert F.
[J]. RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS, 2021, 5 (04)
[3] Population Screening for Von Willebrand Disease in Adolescents with Heavy Menstrual Bleeding
Khamees, Deena
Klima, Jennifer
O'Brien, Sarah H.
[J]. JOURNAL OF PEDIATRICS, 2015, 166 (01): : 195 - 197
[4] HEAVY MENSTRUAL BLEEDING AS AN IMPORTANT PRESENTATION OF VON WILLEBRAND DISEASE IN ADOLESCENTS
Sowa, Anna
Apollonsky, Nataly
[J]. PEDIATRIC BLOOD & CANCER, 2020, 67 : S62 - S63
[5] Prevalence of Von Willebrand Disease among women with Heavy Menstrual Bleeding
Kharab, P.
Sarwan, D.
Goswami, R.
Masih, M.
Ds, P.
Gupta, M.
Chaudhary, V.
Vats, K.
Joyal, W.
Byreddy, P.
John, J.
[J]. HAEMOPHILIA, 2024, 30 : 135 - 136
[6] The Empower Study - Design of a Randomized Clinical Trial to Assess the Efficacy and Safety of a Plasma-Derived Von Willebrand Factor / Factor VIII Concentrate for Heavy Menstrual Bleeding in Women with Von Willebrand Disease
Sholzberg, Michelle
Tang, Grace H.
James, Paula D.
Meffe, Filomena
Rimmer, Emily
Jackson, Shannon
Sun, Haowei Linda
Robinson, Sue
Floros, Georgina
Aratia, Shamshah
Juni, Peter
da Costa, Bruno R.
[J]. BLOOD, 2022, 140 : 8483 - 8484
[7] The Effect of Age on von Willebrand Factor and Bleeding Symptoms in von Willebrand Disease
Seaman, Craig D.
Ragni, Margaret, V
[J]. THROMBOSIS AND HAEMOSTASIS, 2020, 120 (08) : 1159 - 1165
[8] von Willebrand disease and von Willebrand factor
Sadler, Brooke
Castaman, Giancarlo
O'Donnell, James S.
[J]. HAEMOPHILIA, 2022, 28 : 11 - 17
[9] Evaluation of recombinant von Willebrand factor in a canine model of von Willebrand disease
Schwarz, HP
Dorner, F
Mitterer, A
Mundt, W
Schlokat, U
Pichler, L
Turecek, PL
[J]. HAEMOPHILIA, 1998, 4 : 53 - 62
[10] In vivo characterization of recombinant von Willebrand factor in dogs with von Willebrand disease
Turecek, PL
Gritsch, H
Pichler, L
Auer, W
Fischer, B
Mitterer, A
Mundt, W
Schlokat, U
Dorner, F
Erinkman, HJM
vanMourik, JA
Schwarz, HP
[J]. BLOOD, 1997, 90 (09) : 3555 - 3567

← 1 2 3 4 5 →