Chemically defined media for commercial fermentations

被引：142
|
作者：
Zhang, J [1 ]
Greasham, R [1 ]
机构：
[1] Merck Res Labs, Bioproc R&D, Rahway, NJ 07065 USA
来源：
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | 1999年 / 51卷 / 04期
关键词：
D O I：
10.1007/s002530051411
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The use of chemically defined media is gaining popularity in some commercial fermentations, particularly for the preparation of biological products. Although these media are still not frequently developed for industrial processes, they do exhibit favorable characteristics at large scale that are not observed with traditional complex media. This review focuses on the application, development, and practical considerations, especially process economics, of fermentations in chemically defined media in an industrial environment.
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页码：407 / 421
页数：15
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