High resolution imaging of in vivo cardiac dynamics using color Doppler optical coherence tomography

被引：124
|
作者：
Yazdanfar, Siavash [1 ]
Kulkarni, Manish D.
Izatt, Joseph A.
机构：
[1] Case Western Reserve Univ, Dept Biomed Engn, Cleveland, OH 44106 USA
来源：
OPTICS EXPRESS | 1997年 / 1卷 / 13期
基金：
美国国家卫生研究院; 美国国家科学基金会;
关键词：
D O I：
10.1364/OE.1.000424
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
Color Doppler optical coherence tomography (CDOCT) is a noninvasive technique for simultaneous high spatial resolution (similar to 20 mu m) imaging and high velocity resolution (similar to 500 mu m/s) imaging flowmetry in living tissues. In this paper, we demonstrate a reconstruction method which overcomes fundamental limitations on Doppler flow mapping associated with both high-and low-speed imaging. This algorithm is successful in retaining the high velocity resolution of CDOCT while eliminating motion artifact caused by slow image acquisition in samples which exhibit repetitive motion. We demonstrate reconstruction of blood flow throughout a beating Xenopus laevis heart and surrounding vasculature using gated CDOCT reconstruction. (C) 1997 Optical Society of America
引用
收藏
页码：424 / 431
页数：8
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