Palladium-Catalyzed Asymmetric Formal [3+2] Cycloaddition of Vinyl Cyclopropanes and β,γ-Unsaturated α-Keto Esters: An Effective Route to Highly Functionalized Cyclopentanes

被引：84

作者：

Mei, Liang-yong ^{[1
,2
]}

Wei, Yin ^{[3
]}

Xu, Qin ^{[1
,2
]}

Shi, Min ^{[1
,2
,3
]}

机构：

[1] E China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Shanghai 200237, Peoples R China

[2] E China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, Shanghai 200237, Peoples R China

[3] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

ORGANOMETALLICS | 2012年 / 31卷 / 21期

基金：

中国国家自然科学基金;

关键词：

ENANTIOSELECTIVE SYNTHESIS; SUBSTITUTED CYCLOPROPANES; NUCLEOPHILIC-ADDITION; OXAZOLINE LIGANDS; DERIVATIVES; VINYLCYCLOPROPANES; TETRAHYDROFURANS; ACTIVATION; CHEMISTRY;

D O I：

10.1021/om300896z

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Palladium-catalyzed asymmetric formal [3+2] cycloaddition. of vinyl cyclopropanes and beta,gamma-unsaturated alpha-keto esters proceeded smoothly in the presence of chiral imidazoline-phosphine ligands to give the corresponding highly functionalized cyclopentanes in good yields along with high diastereo- and enantioselectivities under mild conditions.

引用

页码：7591 / 7599

页数：9

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