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- [1] A novel small molecule inhibitor to suppress Notch1 activation in CRCCANCER RESEARCH, 2019, 79 (13)Damodaran, Chendil论文数: 0 引用数: 0 h-index: 0机构: Univ Louisville, Louisville, KY 40292 USA Univ Louisville, Louisville, KY 40292 USA论文数: 引用数: h-index:机构:Chandrasekaran, Balaji论文数: 0 引用数: 0 h-index: 0机构: Univ Louisville, Louisville, KY 40292 USA Univ Louisville, Louisville, KY 40292 USA论文数: 引用数: h-index:机构:Jojua, Ibrahim论文数: 0 引用数: 0 h-index: 0机构: Univ Louisville, Louisville, KY 40292 USA Univ Louisville, Louisville, KY 40292 USARamisetti, Srinivasa论文数: 0 引用数: 0 h-index: 0机构: Penn State Univ, Hershey, PA USA Univ Louisville, Louisville, KY 40292 USASharma, Arun K.论文数: 0 引用数: 0 h-index: 0机构: Penn State Univ, Hershey, PA USA Univ Louisville, Louisville, KY 40292 USAAnkem, Murali K.论文数: 0 引用数: 0 h-index: 0机构: Univ Louisville, Louisville, KY 40292 USA Univ Louisville, Louisville, KY 40292 USA
- [2] Disruption of NOTCH signaling by a small molecule inhibitor of the transcription factor RBPJScientific Reports, 9Cecilia Hurtado论文数: 0 引用数: 0 h-index: 0机构: Stanford University,Stanford Cardiovascular Institute and the Department of MedicineAlena Safarova论文数: 0 引用数: 0 h-index: 0机构: Stanford University,Stanford Cardiovascular Institute and the Department of MedicineMichael Smith论文数: 0 引用数: 0 h-index: 0机构: Stanford University,Stanford Cardiovascular Institute and the Department of MedicineRaeeun Chung论文数: 0 引用数: 0 h-index: 0机构: Stanford University,Stanford Cardiovascular Institute and the Department of MedicineArne A. N. Bruyneel论文数: 0 引用数: 0 h-index: 0机构: Stanford University,Stanford Cardiovascular Institute and the Department of MedicineJorge Gomez-Galeno论文数: 0 引用数: 0 h-index: 0机构: Stanford University,Stanford Cardiovascular Institute and the Department of MedicineFranz Oswald论文数: 0 引用数: 0 h-index: 0机构: Stanford University,Stanford Cardiovascular Institute and the Department of MedicineChristopher J. Larson论文数: 0 引用数: 0 h-index: 0机构: Stanford University,Stanford Cardiovascular Institute and the Department of MedicineJohn R. Cashman论文数: 0 引用数: 0 h-index: 0机构: Stanford University,Stanford Cardiovascular Institute and the Department of MedicinePilar Ruiz-Lozano论文数: 0 引用数: 0 h-index: 0机构: Stanford University,Stanford Cardiovascular Institute and the Department of MedicinePhilip Janiak论文数: 0 引用数: 0 h-index: 0机构: Stanford University,Stanford Cardiovascular Institute and the Department of MedicineTeri Suzuki论文数: 0 引用数: 0 h-index: 0机构: Stanford University,Stanford Cardiovascular Institute and the Department of MedicineMark Mercola论文数: 0 引用数: 0 h-index: 0机构: Stanford University,Stanford Cardiovascular Institute and the Department of Medicine
- [3] Disruption of NOTCH signaling by a small molecule inhibitor of the transcription factor RBPJSCIENTIFIC REPORTS, 2019, 9 (1)Hurtado, Cecilia论文数: 0 引用数: 0 h-index: 0机构: Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USA Stanford Univ, Dept Med, Stanford, CA 94305 USA Sanford Burnham Prebys Med Discovery Inst, La Jolla, CA 92037 USA Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USASafarova, Alena论文数: 0 引用数: 0 h-index: 0机构: Icagen, Oro Valley, AZ 85755 USA Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USASmith, Michael论文数: 0 引用数: 0 h-index: 0机构: Icagen, Oro Valley, AZ 85755 USA Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USAChung, Raeeun论文数: 0 引用数: 0 h-index: 0机构: Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USA Stanford Univ, Dept Med, Stanford, CA 94305 USA Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USABruyneel, Arne A. N.论文数: 0 引用数: 0 h-index: 0机构: Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USA Stanford Univ, Dept Med, Stanford, CA 94305 USA Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USAGomez-Galeno, Jorge论文数: 0 引用数: 0 h-index: 0机构: Human BioMol Res Inst, San Diego, CA 92121 USA Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USAOswald, Franz论文数: 0 引用数: 0 h-index: 0机构: Univ Med Ctr Ulm, D-89081 Ulm, Germany Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USALarson, Christopher J.论文数: 0 引用数: 0 h-index: 0机构: Sanford Burnham Prebys Med Discovery Inst, La Jolla, CA 92037 USA Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USACashman, John R.论文数: 0 引用数: 0 h-index: 0机构: Human BioMol Res Inst, San Diego, CA 92121 USA Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USARuiz-Lozano, Pilar论文数: 0 引用数: 0 h-index: 0机构: Regencor, Los Altos, CA 94022 USA Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USAJaniak, Philip论文数: 0 引用数: 0 h-index: 0机构: Sanofi, F-91380 Chilly Mazarin, France Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USASuzuki, Teri论文数: 0 引用数: 0 h-index: 0机构: Icagen, Oro Valley, AZ 85755 USA Belltree Consulting LLC, Tucson, AZ 85745 USA Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USAMercola, Mark论文数: 0 引用数: 0 h-index: 0机构: Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USA Stanford Univ, Dept Med, Stanford, CA 94305 USA Sanford Burnham Prebys Med Discovery Inst, La Jolla, CA 92037 USA Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USA
- [4] Identification of small molecule inhibitors of the notch transcriptional activation complexCANCER RESEARCH, 2017, 77Astudillo, Luisana论文数: 0 引用数: 0 h-index: 0Capobianco, Anthony论文数: 0 引用数: 0 h-index: 0
- [5] Characterization and profiling of CB-103, a novel small-molecule protein-protein interaction inhibitor targeting the NOTCH transcription complexCANCER RESEARCH, 2018, 78 (13)Lehal, Rajwinder论文数: 0 引用数: 0 h-index: 0机构: Cellestia Biotech AG, Basel, Switzerland Cellestia Biotech AG, Basel, SwitzerlandUrech, Charlotte论文数: 0 引用数: 0 h-index: 0机构: Cellestia Biotech AG, Basel, Switzerland Cellestia Biotech AG, Basel, SwitzerlandVigolo, Michele论文数: 0 引用数: 0 h-index: 0机构: Ecole Polytech Fed Lausanne, Lausanne, Switzerland Cellestia Biotech AG, Basel, SwitzerlandMurone, Maximilien论文数: 0 引用数: 0 h-index: 0机构: Cellestia Biotech AG, Basel, Switzerland Cellestia Biotech AG, Basel, SwitzerlandRadtke, Freddy论文数: 0 引用数: 0 h-index: 0机构: Ecole Polytech Fed Lausanne, Lausanne, Switzerland Cellestia Biotech AG, Basel, Switzerland
- [6] Target engagement and clinical safety of CB-103, a first-in-class small molecule inhibitor of the NOTCH transcription complexANNALS OF ONCOLOGY, 2020, 31 : S484 - S485Azaro Pedrazzoli, A. B.论文数: 0 引用数: 0 h-index: 0机构: Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, Spain Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainPerez Garcia, J. M.论文数: 0 引用数: 0 h-index: 0机构: Hosp Quironsalud Barcelona, Dept Med Oncol, Barcelona, Spain Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainCortes, J.论文数: 0 引用数: 0 h-index: 0机构: IOB Inst Oncol, Dept Oncol, Quironsalud Grp, Madrid, Spain IOB Inst Oncol, Dept Oncol, Quironsalud Grp, Barcelona, Spain Vall dHebron Inst Oncol VHIO, Barcelona, Spain Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainLopez Miranda, E.论文数: 0 引用数: 0 h-index: 0机构: Hosp Univ Ramon & Cajal, Med Oncol, Madrid, Spain Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainColombo, I.论文数: 0 引用数: 0 h-index: 0机构: EOC Osped Reg Bellinzona & Valli, Med Oncol, Bellinzona, Switzerland Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainGarralda, E.论文数: 0 引用数: 0 h-index: 0机构: Vall dHebron Inst Oncol VHIO, Early Drug Dev Unit UITM), Barcelona, Spain Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainHess, D.论文数: 0 引用数: 0 h-index: 0机构: Kantonsspital St Gallen, Dept Med Oncol, St Gallen, Switzerland Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainNuciforo, P. G.论文数: 0 引用数: 0 h-index: 0机构: Vall dHebron Inst Oncol VHIO, Canc Genom, Cellex Ctr, Barcelona, Spain Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainVivancos, A.论文数: 0 引用数: 0 h-index: 0机构: Vall dHebron Inst Oncol VHIO, Canc Genom, Barcelona, Spain Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainFerrarotto, R.论文数: 0 引用数: 0 h-index: 0机构: Univ Texas Hlth Sci Ctr Houston, Thorac Head & Neck Med Oncol, Houston, TX 77030 USA Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainSchoenborn-Kellenberger, O.论文数: 0 引用数: 0 h-index: 0机构: Cogitars GmbH, Stat, Heidelberg, Germany Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainJorga, K.论文数: 0 引用数: 0 h-index: 0机构: KarinJorga Life Sci Consulting, Pharmacokinet, Basel, Switzerland Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainVigolo, M.论文数: 0 引用数: 0 h-index: 0机构: Cellestia Biotech AG, R&D, Epalinges, Switzerland Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainBeni, L.论文数: 0 引用数: 0 h-index: 0机构: Cellestia Biotech AG, Dev, Basel, Switzerland Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainLehal, R.论文数: 0 引用数: 0 h-index: 0机构: Cellestia Biotech AG, Dev, Basel, Switzerland Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainMurone, M.论文数: 0 引用数: 0 h-index: 0机构: Cellestia Biotech AG, Dev, Basel, Switzerland Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainBauer, M.论文数: 0 引用数: 0 h-index: 0机构: Cellestia Biotech AG, Dev, Basel, Switzerland Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainPisa, P.论文数: 0 引用数: 0 h-index: 0机构: Cellestia Biotech AG, Dev, Basel, Switzerland Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainVogl, F. D.论文数: 0 引用数: 0 h-index: 0机构: Cellestia Biotech AG, Dev, Basel, Switzerland Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, SpainStathis, A.论文数: 0 引用数: 0 h-index: 0机构: EOC Osped Reg Bellinzona & Valli, Med Oncol, Bellinzona, Switzerland Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Mol Therapeut Res Unit UITM, Barcelona, Spain
- [7] The Notch transcription activation complex makes its moveCELL, 2006, 124 (05) : 883 - 885Barrick, D论文数: 0 引用数: 0 h-index: 0机构: Johns Hopkins Univ, TC Jenkins Dept Biophys, Baltimore, MD 21218 USAKopan, R论文数: 0 引用数: 0 h-index: 0机构: Johns Hopkins Univ, TC Jenkins Dept Biophys, Baltimore, MD 21218 USA
- [8] The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress TumorigenesisCANCER RESEARCH, 2016, 76 (12) : 3593 - 3603Astudillo, Luisana论文数: 0 引用数: 0 h-index: 0机构: Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USA Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Miami, FL 33136 USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USADa Silva, Thiago G.论文数: 0 引用数: 0 h-index: 0机构: Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USA Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Miami, FL 33136 USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USAWang, Zhiqiang论文数: 0 引用数: 0 h-index: 0机构: Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USA Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Miami, FL 33136 USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USAHan, Xiaoqing论文数: 0 引用数: 0 h-index: 0机构: Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USA Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Miami, FL 33136 USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USAJin, Ke论文数: 0 引用数: 0 h-index: 0机构: Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USA Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Miami, FL 33136 USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USAVanWye, Jeffrey论文数: 0 引用数: 0 h-index: 0机构: Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USA Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Miami, FL 33136 USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USAZhu, Xiaoxia论文数: 0 引用数: 0 h-index: 0机构: Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USA Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Miami, FL 33136 USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USAWeaver, Kelly论文数: 0 引用数: 0 h-index: 0机构: Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USA Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Miami, FL 33136 USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USAOashi, Taiji论文数: 0 引用数: 0 h-index: 0机构: Univ Maryland, Sch Pharm, Dept Pharmaceut Sci, Baltimore, MD 21201 USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USALopes, Pedro E. M.论文数: 0 引用数: 0 h-index: 0机构: Univ Maryland, Sch Pharm, Dept Pharmaceut Sci, Baltimore, MD 21201 USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USAOrton, Darren论文数: 0 引用数: 0 h-index: 0机构: StemSynergy Therapeut Inc, Miami, FL USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USANeitzel, Leif R.论文数: 0 引用数: 0 h-index: 0机构: Vanderbilt Univ, Med Ctr, Dept Cell & Dev Biol, Nashville, TN USA Vanderbilt Univ, Med Ctr, Ingram Canc Ctr, Nashville, TN USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USALee, Ethan论文数: 0 引用数: 0 h-index: 0机构: Vanderbilt Univ, Med Ctr, Dept Cell & Dev Biol, Nashville, TN USA Vanderbilt Univ, Med Ctr, Ingram Canc Ctr, Nashville, TN USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USALandgraf, Ralf论文数: 0 引用数: 0 h-index: 0机构: Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Miami, FL 33136 USA Univ Miami, Dept Biochem & Mol Biol, Miami, FL 33136 USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USARobbins, David J.论文数: 0 引用数: 0 h-index: 0机构: Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USA Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Miami, FL 33136 USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USAMacKerell, Alexander D., Jr.论文数: 0 引用数: 0 h-index: 0机构: Univ Maryland, Sch Pharm, Dept Pharmaceut Sci, Baltimore, MD 21201 USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USACapobianco, Anthony J.论文数: 0 引用数: 0 h-index: 0机构: Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USA Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Miami, FL 33136 USA Univ Miami, Dewitt Daughtry Family Dept Surg, Mol Oncol Program, Div Surg Oncol, Miami, FL 33136 USA
- [9] Direct targeting of NOTCH transcription complex by a novel small molecule CB-103 circumvents dose-limiting toxicities associated with pan-NOTCH inhibitorsCANCER RESEARCH, 2019, 79 (13)Lehal, Rajwinder论文数: 0 引用数: 0 h-index: 0机构: Ecole Polytech Fed Lausanne, Lausanne, Switzerland Ecole Polytech Fed Lausanne, Lausanne, SwitzerlandZaric, Jelena论文数: 0 引用数: 0 h-index: 0机构: Ecole Polytech Fed Lausanne, Lausanne, Switzerland Ecole Polytech Fed Lausanne, Lausanne, SwitzerlandVigolo, Michele论文数: 0 引用数: 0 h-index: 0机构: Ecole Polytech Fed Lausanne, Lausanne, Switzerland Ecole Polytech Fed Lausanne, Lausanne, SwitzerlandUrech, Charlotte论文数: 0 引用数: 0 h-index: 0机构: Cellestia Biotech AG, Basel, Switzerland Ecole Polytech Fed Lausanne, Lausanne, SwitzerlandMurone, Maximilien论文数: 0 引用数: 0 h-index: 0机构: Cellestia Biotech AG, Basel, Switzerland Ecole Polytech Fed Lausanne, Lausanne, SwitzerlandRadtke, Freddy论文数: 0 引用数: 0 h-index: 0机构: Ecole Polytech Fed Lausanne, Lausanne, Switzerland Ecole Polytech Fed Lausanne, Lausanne, Switzerland
- [10] Activation of gene expression by small molecule transcription factorsPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (08) : 3930 - 3935Mapp, AK论文数: 0 引用数: 0 h-index: 0机构: CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USAAnsari, AZ论文数: 0 引用数: 0 h-index: 0机构: CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USAPtashne, M论文数: 0 引用数: 0 h-index: 0机构: CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USADervan, PB论文数: 0 引用数: 0 h-index: 0机构: CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USA CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USA