Integrative database analysis in structural genomics

被引:41
|
作者
Gerstein, M [1 ]
机构
[1] Yale Univ, Dept Mol Biophys & Biochem, New Haven, CT 06520 USA
关键词
D O I
10.1038/80739
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
An important aspect of structural genomics is connecting coordinate data with whole-genome information related to phylogenetic occurrence, protein function, gene expression, and protein-protein interactions. Integrative database analysis allows one to survey the 'finite parts list' of protein folds from many perspectives, highlighting certain folds and structural features that stand out in particular ways.
引用
收藏
页码:960 / 963
页数:4
相关论文
共 50 条
  • [1] Integrative database analysis in structural genomics
    Mark Gerstein
    Nature Structural Biology, 2000, 7 : 960 - 963
  • [2] The PRESAGE database for structural genomics
    Brenner, SE
    Barken, D
    Levitt, M
    NUCLEIC ACIDS RESEARCH, 1999, 27 (01) : 251 - 253
  • [3] The SUPERFAMILY database in structural genomics
    Gough, J
    ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 2002, 58 : 1897 - 1900
  • [4] LegumeIP: an integrative database for comparative genomics and transcriptomics of model legumes
    Li, Jun
    Dai, Xinbin
    Liu, Tingsong
    Zhao, Patrick Xuechun
    NUCLEIC ACIDS RESEARCH, 2012, 40 (D1) : D1221 - D1229
  • [5] Integrative Analysis of Heterogeneous Genomics Data
    Zhou, Xianghong Jasmine
    COMPUTATIONAL SYSTEMS BIOLOGY, 2010, 13 : 9 - 9
  • [6] TOPSAN: a dynamic web database for structural genomics
    Ellrott, Kyle
    Zmasek, Christian M.
    Weekes, Dana
    Krishna, S. Sri
    Bakolitsa, Constantina
    Godzik, Adam
    Wooley, John
    NUCLEIC ACIDS RESEARCH, 2011, 39 : D494 - D496
  • [7] Rice Annotation Project Database (RAP-DB): An Integrative and Interactive Database for Rice Genomics
    Sakai, Hiroaki
    Lee, Sung Shin
    Tanaka, Tsuyoshi
    Numa, Hisataka
    Kim, Jungsok
    Kawahara, Yoshihiro
    Wakimoto, Hironobu
    Yang, Ching-chia
    Iwamoto, Masao
    Abe, Takashi
    Yamada, Yuko
    Muto, Akira
    Inokuchi, Hachiro
    Ikemura, Toshimichi
    Matsumoto, Takashi
    Sasaki, Takuji
    Itoh, Takeshi
    PLANT AND CELL PHYSIOLOGY, 2013, 54 (02) : E6 - +
  • [8] Integrative analysis and machine learning on cancer genomics data using the Cancer Systems Biology Database (CancerSysDB)
    Rasmus Krempel
    Pranav Kulkarni
    Annie Yim
    Ulrich Lang
    Bianca Habermann
    Peter Frommolt
    BMC Bioinformatics, 19
  • [9] Integrative analysis and machine learning on cancer genomics data using the Cancer Systems Biology Database (CancerSysDB)
    Krempel, Rasmus
    Kulkarni, Pranav
    Yim, Annie
    Lang, Ulrich
    Habermann, Bianca
    Frommolt, Peter
    BMC BIOINFORMATICS, 2018, 19
  • [10] Integrative cancer genomics: models, algorithms and analysis
    Chen, Jinyu
    Zhang, Shihua
    FRONTIERS OF COMPUTER SCIENCE, 2017, 11 (03) : 392 - 406