A Mild, Selective Copper-Catalyzed Oxidative Phosphonation of α-Amino Ketones

被引：94
|
作者：
Yang, Bin [1 ]
Yang, Ting-Ting [1 ]
Li, Xi-An [1 ]
Wang, Jun-Jiao [1 ]
Yang, Shang-Dong [1 ,2 ]
机构：
[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
[2] Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China
来源：
ORGANIC LETTERS | 2013年 / 15卷 / 19期
关键词：
C-H BOND; DEHYDROGENATIVE-COUPLING CDC; TERTIARY-AMINES; NITROGEN ATOM; MOLECULAR-OXYGEN; TERMINAL ALKYNES; ADJACENT; METAL; ACTIVATION; IMINES;
D O I：
10.1021/ol402355a
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel and selective method of simple copper-salt catalyzed phosphonation of alpha-amino carbonyl compounds to afford imidoylphosphonates is reported. This reaction system has a broad reaction scope. The convenient and environmentally benign process makes this protocol very attractive.
引用
收藏
页码：5024 / 5027
页数：4
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