RADICAL SCAVENGING ACTIVITY OF SELECTED MEDICINAL PLANTS FROM LIMPOPO PROVINCE OF SOUTH AFRICA

被引：13

作者：

Chauke, A. M. ^{[1
]}

Shai, L. J. ^{[1
]}

Mphahlele, P. M. ^{[1
]}

Mogale, M. A. ^{[2
]}

机构：

[1] Tshwane Univ Technol, Fac Sci, Dept Biomed Sci, ZA-0001 Pretoria, South Africa

[2] Univ Limpopo, Fac Med, Dept Physiol, ZA-0204 Medunsa, South Africa

来源：

AFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINES | 2012年 / 9卷 / 03期

基金：

新加坡国家研究基金会;

关键词：

antioxidant activity; medicinal plants; DPPH; phenolics; ANTIOXIDANT ACTIVITY; BERGENIN;

D O I：

10.4314/ajtcam.v9i3.19

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Plants collected from Limpopo province of South Africa were investigated for their antioxidative potential using the DPPH radical scavenging assay. Acetone extracts of Flueggea virosa had the highest antioxidant activity with an IC50 value of 30 mu g/ml, closely matching the ascorbic acid with an IC50 value of 25 mu g/ml. The lowest antioxidant readings were observed with extracts of Rhynchosia venulosa (root extract) and Ficus ingens (leaf extract). Acetone extract of Bridelia virosa leaves had the highest phenolic content (156 mg GAE/g extract), while the lowest content was recorded for R. venulosa root extract and leaf extract of F. ingens (8.3 and 17.7 mg GAE/g extract, respectively). There was a linear correlation between antioxidant activity and total phenolic content. Extracts with high phenolic content had low IC50 values, while extracts with low phenolic concentrations had high IC50 values.

引用

页码：426 / 430

页数：5

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