Discovery and clinical progression of highly selective M1 agonists utilizing structure-based drug design

被引：0
|
作者：
Brown, Giles [1 ]
机构：
[1] Heptares Therapeut Ltd, Cambrdige, England
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2017年 / 254卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
244
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Structure-Based Design and Discovery of New M2 Receptor Agonists
    Fish, Inbar
    Stoessel, Anne
    Eitel, Katrin
    Valant, Celine
    Albold, Sabine
    Huebner, Harald
    Moeller, Dorothee
    Clark, Mary J.
    Sunahara, Roger K.
    Christopoulos, Arthur
    Shoichet, Brian K.
    Gmeiner, Peter
    JOURNAL OF MEDICINAL CHEMISTRY, 2017, 60 (22) : 9239 - 9250
  • [2] Progression in structure-based drug design
    Fong, F
    GENETIC ENGINEERING NEWS, 2004, 24 (07): : 26 - +
  • [3] Structure-based discovery of potent and selective melatonin receptor agonists
    Patel, Nilkanth
    Huang, Xi Ping
    Grandner, Jessica M.
    Johansson, Linda C.
    Stauch, Benjamin
    McCorvy, John D.
    Liu, Yongfeng
    Roth, Bryan
    Katritch, Vsevolod
    ELIFE, 2020, 9
  • [4] Discovery and structure-based design of a new series of potent and selective PPAR6 agonists utilizing a virtual screening method
    Kato, Terukazu
    Ohara, Takafumi
    Suzuki, Naoyuki
    Muto, Susumu
    Tokuyama, Ryukou
    Mizutani, Miho
    Fukasawa, Hiroshi
    Matsumura, Ken-ichi
    Itai, Akiko
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 59
  • [5] Antibacterial drug discovery and structure-based design
    Barker, John J.
    DRUG DISCOVERY TODAY, 2006, 11 (9-10) : 391 - 404
  • [6] Structure-based Design on Anticancer Drug Discovery
    Zhong, Haizhen Andrew
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2020, 20 (10) : 813 - 814
  • [7] Structure-based screening and design in drug discovery
    van Dongen, M
    Weigelt, J
    Uppenberg, J
    Schultz, J
    Wikström, M
    DRUG DISCOVERY TODAY, 2002, 7 (08) : 471 - 478
  • [8] STRUCTURE-BASED STRATEGIES FOR DRUG DESIGN AND DISCOVERY
    KUNTZ, ID
    SCIENCE, 1992, 257 (5073) : 1078 - 1082
  • [9] Discovery of a novel class of selective muscarinic M1 agonists suitable for clinical development.
    Hitchcock, S
    Allen, J
    Baker, A
    Bensinger, J
    Bick, P
    Bymaster, F
    Delapp, N
    Gannon, K
    Gregory, GS
    Hansen, M
    Hoogestraat, P
    Jamison, J
    Kher, S
    Kolis, S
    Liu, B
    Ohka, F
    Mckinzie, D
    Rao, ZG
    Stratford, R
    Turner, W
    Felder, CC
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2003, 225 : U233 - U233
  • [10] Enabling structure-based drug discovery utilizing predicted models
    Miller, Edward B.
    Hwang, Howook
    Shelley, Mee
    Placzek, Andrew
    Rodrigues, Joao P. G. L. M.
    Suto, Robert K.
    Wang, Lingle
    Akinsanya, Karen
    Abel, Robert
    CELL, 2024, 187 (03)
12345