A new pyrrole alkaloid from Selaginella moellendorfii Hieron

被引：9

作者：

Zou, Zhen-Xing ^{[1
]}

Xu, Kang-Ping ^{[1
]}

Li, Fu-Shuang ^{[1
]}

Zou, Hui ^{[1
]}

Liu, Min-Zhen ^{[1
]}

Zhang, Qiong ^{[1
]}

Yu, Kai ^{[1
]}

Zhao, Lan-Fang ^{[1
]}

Tan, Lei-Hong ^{[1
]}

Tan, Gui-Shan ^{[1
,2
]}

机构：

[1] Cent S Univ, Sch Pharmaceut Sci, Changsha 410013, Hunan, Peoples R China

[2] Cent S Univ, Xiangya Hosp, Changsha 410008, Hunan, Peoples R China

来源：

CHINESE CHEMICAL LETTERS | 2013年 / 24卷 / 02期

关键词：

Selaginella; Selaginella moellendorfii Hieron; Pyrrole alkaloid; HUVECs; NATURAL PIGMENT; DERIVATIVES; TAMARISCINA; PULVINATA;

D O I：

10.1016/j.cclet.2013.01.028

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

One new pyrrole alkaloid, N-(2E)-3-(3,4-dihydrophenyl)prop-N-1'-(4-aminobutyl)-3-pyrrole formaldehyde (1), was isolated from the whole herbs of Selaginella moellendorfii Hieron. The structure was elucidated by spectroscopic analyses including UV, IR, 1D NMR, 2D NMR and MS methods. Additionally, compound 1 exhibited potent protective effect against the injury of human umbilical vein endothelial cell (HUVECs) induced by high concentrations of glucose in vitro. (C) 2013 Gui-Shan Tan. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

引用

页码：114 / 116

页数：3

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