Inhibition of lysine63 ubiquitination prevents in vitro and in vivo the progression of renal fibrosis in diabetic nephropathy

被引：0
|
作者：
Pontrelli, P. [1 ]
Menghini, R. [2 ]
Conserva, F. [1 ]
Casagrande, V. [2 ]
Rossini, M. [1 ]
Stasi, A. [1 ]
Divella, C. [1 ]
Cinefra, C. [1 ]
Simone, S. [1 ]
Pertosa, G. [1 ]
Gallone, A. [3 ]
Federici, M. [2 ]
Gesualdo, L. [1 ]
机构：
[1] Univ Bari Aldo Moro, Dept Emergency & Organ Transplantat, Bari, Italy
[2] Univ Roma Tor Vergata, Dept Syst Med, Rome, Italy
[3] Univ Bari Aldo Moro, Dept Basic Med Sci Neurosci & Sense Organs, Bari, Italy
来源：
DIABETOLOGIA | 2020年 / 63卷 / SUPPL 1期
基金：
欧盟地平线“2020”;
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
137
引用
收藏
页码：S69 / S69
页数：1
相关论文
共 50 条
  • [1] INHIBITION OF LYSINE63 UBIQUITINATION PREVENTS THE PROGRESSION OF RENAL FIBROSIS IN DIABETIC NEPHROPATHY IN VITRO AND IN VIVO
    Conserva, Francesca
    Pontrelli, Paola
    Menghini, Rossella
    Rossini, Michele
    Stasi, Alessandra
    Divella, Chiara
    Cinefra, Claudia
    Simone, Simona
    Pertosa, Giovanni Battista
    Gallone, Anna
    Federici, Massimo
    Gesualdo, Loreto
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2020, 35 : 1295 - 1295
  • [2] Inhibition of Lysine 63 Ubiquitination Prevents the Progression of Renal Fibrosis in Diabetic DBA/2J Mice
    Pontrelli, Paola
    Conserva, Francesca
    Menghini, Rossella
    Rossini, Michele
    Stasi, Alessandra
    Divella, Chiara
    Casagrande, Viviana
    Cinefra, Claudia
    Barozzino, Mariagrazia
    Simone, Simona
    Pesce, Francesco
    Castellano, Giuseppe
    Stallone, Giovanni
    Gallone, Anna
    Giorgino, Francesco
    Federici, Massimo
    Gesualdo, Loreto
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (10)
  • [3] Lysine 63 ubiquitination is involved in the progression of tubular damage in diabetic nephropathy
    Pontrelli, Paola
    Conserva, Francesca
    Papale, Massimo
    Oranger, Annarita
    Barozzino, Mariagrazia
    Vocino, Grazia
    Rocchetti, Maria Teresa
    Gigante, Margherita
    Castellano, Giuseppe
    Rossini, Michele
    Simone, Simona
    Laviola, Luigi
    Giorgino, Francesco
    Grandaliano, Giuseppe
    Di Paolo, Salvatore
    Gesualdo, Loreto
    FASEB JOURNAL, 2017, 31 (01): : 308 - 319
  • [4] Deregulation of autophagy under hyperglycemic conditions is dependent on increased lysine 63 ubiquitination: a candidate mechanism in the progression of diabetic nephropathy
    Pontrelli, Paola
    Oranger, Annarita
    Barozzino, Mariagrazia
    Divella, Chiara
    Conserva, Francesca
    Fiore, Maria Grazia
    Rossi, Roberta
    Papale, Massimo
    Castellano, Giuseppe
    Simone, Simona
    Laviola, Luigi
    Giorgino, Francesco
    Piscitelli, Domenico
    Gallone, Anna
    Gesualdo, Loreto
    JOURNAL OF MOLECULAR MEDICINE-JMM, 2018, 96 (07): : 645 - 659
  • [5] Deregulation of autophagy under hyperglycemic conditions is dependent on increased lysine 63 ubiquitination: a candidate mechanism in the progression of diabetic nephropathy
    Paola Pontrelli
    Annarita Oranger
    Mariagrazia Barozzino
    Chiara Divella
    Francesca Conserva
    Maria Grazia Fiore
    Roberta Rossi
    Massimo Papale
    Giuseppe Castellano
    Simona Simone
    Luigi Laviola
    Francesco Giorgino
    Domenico Piscitelli
    Anna Gallone
    Loreto Gesualdo
    Journal of Molecular Medicine, 2018, 96 : 645 - 659
  • [6] SGLT2 INHIBITION PREVENTS RENAL FIBROSIS IN CYCLOSPORINE NEPHROPATHY
    Castoldi, Giovanna
    Carletti, Raffaella
    Ippolito, Silvia
    Colzani, Massimiliano
    Barzaghi, Francesca
    Stella, Andrea
    Zerbini, Gianpaolo
    Perseghin, Gianluca
    Zatti, Giovanni
    Di Gioia, Cira
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2020, 35 : 1307 - 1307
  • [7] Puerarin prevents diabetic cardiomyopathy in vivo and in vitro by inhibition of inflammation
    Yin, Mao-Shan
    Zhang, Yi-Chi
    Xu, Shu-Hong
    Liu, Jing-Jing
    Sun, Xiao-Hui
    Liang, Chen
    Wang, Yan
    Li, Jie
    Wang, Fu-Wen
    Wang, Qing-Li
    Mu, Yan-Ling
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 21 (05) : 476 - 493
  • [8] Dietary low-fat soy milk powder retards diabetic nephropathy progression via inhibition of renal fibrosis and renal inflammation
    Jheng, Huei-Fen
    Hirotsuka, Motohiko
    Goto, Tsuyoshi
    Shibata, Masayuki
    Matsumura, Yasuki
    Kawada, Teruo
    MOLECULAR NUTRITION & FOOD RESEARCH, 2017, 61 (03)
  • [9] Sodium-glucose cotransporter 2 inhibition prevents renal fibrosis in cyclosporine nephropathy
    Castoldi, Giovanna
    Carletti, Raffaella
    Ippolito, Silvia
    Colzani, Massimiliano
    Barzaghi, Francesca
    Stella, Andrea
    Zerbini, Gianpaolo
    Perseghin, Gianluca
    Zatti, Giovanni
    di Gioia, Cira R. T.
    ACTA DIABETOLOGICA, 2021, 58 (08) : 1059 - 1070
  • [10] NUP160 knockdown inhibits the progression of diabetic nephropathy in vitro and in vivo
    Xie, Jiayong
    Chen, Zhi
    Yao, Gang
    Yuan, Ying
    Yu, Wenjuan
    Zhu, Qiang
    REGENERATIVE THERAPY, 2022, 21 : 87 - 95
12345