Epidemiological aspects of HCV infection in HIV-infected individuals in Piaui State, Northeast Brazil

被引：8
|
作者：
Oliveira-Filho, Aldemir B. [1 ,2 ]
Oliveira, Evaldo H. [3 ]
Castro, Jairo A. A. [2 ]
Silva, Letiano V. [4 ]
Vallinoto, Antonio C. R. [5 ]
Lemos, Jose Alexandre R. [2 ,5 ]
机构：
[1] Fed Univ Para, Fac Ciencias Nat, Breves, PA, Brazil
[2] Ctr Hematol & Hemoterapia, Lab Biol Mol, Belem, PA, Brazil
[3] Univ Fed Piaui, Ctr Ciencias Saude, Teresina, PI, Brazil
[4] Lab Cent Saude Publ Piaui, Teresina, PI, Brazil
[5] Fed Univ Para, Lab Virol, Inst Ciencias Biol, Belem, PA, Brazil
来源：
ARCHIVES OF VIROLOGY | 2012年 / 157卷 / 12期
关键词：
HCV; HIV; Coinfection; Epidemiology; Brazil; HEPATITIS-C VIRUS; INJECTING DRUG-USERS; PREVALENCE; GENOTYPES; RISK;
D O I：
10.1007/s00705-012-1435-3
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
In this study, the prevalence, genotypic frequency, and risk factors for HCV infection in 768 patients infected with HIV were determined. Fifty-two (6.77 %) HIV-positive individuals had anti-HCV antibodies and 26 (3.39 %) had HCV-RNA. Genotyping results indicated that all RT-PCR samples from patients infected with HCV belonged to genotype 1. Multivariate analysis revealed an association of HIV-HCV coinfection with drug use and having received blood transfusions before 1994. The relatively low prevalence of HCV infection in the HIV-positive population in that region may be a consequence of the small number of drug users in the sample, despite a strong association between HCV infection and drug use.
引用
收藏
页码：2411 / 2416
页数：6
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