Advances in characterisation and biological activities of chitosan and chitosan oligosaccharides

被引：336
|
作者：
Zou, Pan [1 ,2 ]
Yang, Xin [1 ,2 ]
Wang, Jing [1 ,2 ,3 ]
Li, Yongfei [2 ,3 ]
Yu, Hailong [2 ,3 ]
Zhang, Yanxin [1 ,2 ]
Liu, Guangyang [1 ,2 ]
机构：
[1] Harbin Inst Technol, Sch Chem Engn & Technol, Dept Food Sci & Engn, Harbin 150090, Heilongjiang Pr, Peoples R China
[2] Chinese Acad Agr Sci, Inst Qual Stand & Testing Technol Agroprod, Key Lab Agroprod Qual & Safety, Beijing 100081, Peoples R China
[3] Minist Agr, Key Lab Agrifood Safety & Qual, Beijing 100081, Peoples R China
来源：
FOOD CHEMISTRY | 2016年 / 190卷
基金：
中国国家自然科学基金;
关键词：
Chitosan; Chitosan oligosaccharides; Biological activities; Physicochemical; Anti-tumour; Mechanism; MOLECULAR-WEIGHT CHITOSAN; HEXA-N-ACETYLCHITOHEXAOSE; WATER-SOLUBLE CHITOSAN; ANTIMICROBIAL ACTIVITY; ANTIBACTERIAL ACTIVITY; BIOMEDICAL APPLICATIONS; ENZYMATIC-HYDROLYSIS; ANTICANCER ACTIVITY; SURFACE-CHARGE; CHITOOLIGOSACCHARIDES;
D O I：
10.1016/j.foodchem.2015.06.076
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Chitosan and chitosan oligosaccharides (COS) have been reported to possess various biomedical properties, including antimicrobial activities, immuno-enhancing effects, and anti-tumour activities. COS have attracted considerable interest due to their physicochemical properties, and potential applications in the food and pharmaceutical industries, especially in cancer therapies. This paper describes the preparation of COS and their physicochemical properties, and modification, which aids understanding of their biological activities. Based on the latest reports, several biological and anti-tumour activities of COS will be discussed. The proposed anti-tumour mechanisms of COS are summarised, to provide comprehensive insights into research on the molecular level. Finally, the potential applications and future development of the biopolymer will be discussed. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1174 / 1181
页数：8
相关论文
共 50 条
  • [1] Preparation and biological activities of chitosan oligosaccharides
    Benchamas, Gunsriwiang
    Huang, Gangliang
    Huang, Shiyu
    Huang, Hualiang
    TRENDS IN FOOD SCIENCE & TECHNOLOGY, 2021, 107 : 38 - 44
  • [2] Research Advances in Chitosan Oligosaccharides: From Multiple Biological Activities to Clinical Applications
    Yi, Zhen
    Luo, Xiao
    Zhao, Lei
    CURRENT MEDICINAL CHEMISTRY, 2020, 27 (30) : 5037 - 5055
  • [3] Advances in the preparation and assessment of the biological activities of chitosan oligosaccharides with different structural characteristics
    Zhou, Jingwen
    Wen, Bingjian
    Xie, Hongyi
    Zhang, Chengcheng
    Bai, Yan
    Cao, Hua
    Che, Qishi
    Guo, Jiao
    Su, Zhengquan
    FOOD & FUNCTION, 2021, 12 (03) : 926 - 951
  • [4] Enzymatic production and biological activities of chitosan oligosaccharides (COS): A review
    Kim, SK
    Rajapakse, N
    CARBOHYDRATE POLYMERS, 2005, 62 (04) : 357 - 368
  • [5] Biological activities of chitosan and chitooligosaccharides
    Xia, Wenshui
    Liu, Ping
    Zhang, Jiali
    Chen, Jie
    FOOD HYDROCOLLOIDS, 2011, 25 (02) : 170 - 179
  • [6] Physiological activities and efficient production processes of chitosan oligosaccharides
    Kuroiwa, T
    Ichikawa, S
    Sato, S
    Mukataka, S
    JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI, 2005, 52 (07): : 285 - 296
  • [7] The Microstructure, Antibacterial and Antitumor Activities of Chitosan Oligosaccharides and Derivatives
    Yu, Dawei
    Feng, Jiayao
    You, Huimin
    Zhou, Shipeng
    Bai, Yan
    He, Jincan
    Cao, Hua
    Che, Qishi
    Guo, Jiao
    Su, Zhengquan
    MARINE DRUGS, 2022, 20 (01)
  • [8] Biological Effects and Applications of Chitosan and Chito-Oligosaccharides
    Guan, Guiping
    Azad, Md. Abul Kalam
    Lin, Yuanshan
    Kim, Sung Woo
    Tian, Yun
    Liu, Gang
    Wang, Hongbing
    FRONTIERS IN PHYSIOLOGY, 2019, 10
  • [9] Effect of molecular weight of chitosan and its oligosaccharides on antitumor activities of chitosan-selenium nanoparticles
    Song, Xiaoxiao
    Chen, Yuying
    Zhao, Guanghua
    Sun, Hongbo
    Che, Huilian
    Leng, Xiaojing
    CARBOHYDRATE POLYMERS, 2020, 231 (231)
  • [10] Advances in extraction and biological activities of crawfish chitosan and its application in decolorization of synthetic dyes
    Hamdi, S. A.
    Zahran, A. K.
    Abou-Taleb, M. A.
    Heikel, A. M.
    Abou El-Kheir, M. T.
    Abou-Zeid, N. H.
    Haggag, D. A.
    Aloufi, A. S.
    Elbaz, R. M.
    Abd El-Ghany, M. N.
    ARQUIVO BRASILEIRO DE MEDICINA VETERINARIA E ZOOTECNIA, 2024, 76 (06)
12345