Outbreak of delta variant SARS-CoV-2 virus on a psychogeriatric ward in Helsinki, Finland, August 2021: two-dose vaccination reduces mortality and disease severity amongst the elderly

被引:1
|
作者
Malik, Adnan [1 ]
Lehtola, Laura [2 ]
Isosomppi, Sanna [3 ]
Smura, Teemu [4 ]
Saarenheimo, Jaana [1 ]
Anttila, Veli-Jukka [2 ]
Sarela, Eeva [3 ]
机构
[1] Suursuo Hosp, Social Serv & Healthcare Div, Helsinki, Finland
[2] Helsinki Univ Hosp, Infect Dis Unit, Helsinki, Finland
[3] Social Serv & Healthcare Div, Epidemiol Operat Unit, Helsinki, Finland
[4] Univ Helsinki, Fac Med, Dept Virol, Helsinki, Finland
来源
EPIDEMIOLOGY AND INFECTION | 2022年 / 150卷
关键词
corona; Covid; 19; vaccination; geriatrics; inpatient;
D O I
10.1017/S0950268822000589
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
We describe an outbreak of delta variant SARS-CoV-2 on a psychogeriatric ward of elderly patients. Retrospectively collected data was analysed using Fisher's exact test to assess the association between patients' vaccination status and infection rates, severity of disease and mortality. Vaccination with two doses was shown to reduce severity of disease (5% vs. 75%, p < 0.001) and mortality (5% vs. 50%, p < 0.018) amongst an elderly inpatient population during an outbreak of delta variant SARS-CoV-2. Vaccination should be encouraged in elderly care institutions. Furthermore, adequate vaccination in elderly care institutions is an important consideration in current booster (third/fourth) dose schedules.
引用
收藏
页数:5
相关论文
共 15 条
  • [1] August 2021 and the Delta variant: is mandatory vaccination of individuals against SARS-CoV-2 acceptable?
    Dal-Re, Rafael
    Camps, Victoria
    MEDICINA CLINICA, 2022, 158 (05): : 233 - 236
  • [2] An outbreak caused by the SARS-CoV-2 Delta variant (B.1.617.2) in a secondary care hospital in Finland, May 2021
    Hetemaki, Iivo
    Kaariainen, Sohvi
    Alho, Pirjo
    Mikkola, Janne
    Savolainen-Kopra, Carita
    Ikonen, Niina
    Nohynek, Hanna
    Lyytikainen, Outi
    EUROSURVEILLANCE, 2021, 26 (30)
  • [3] Disease Flare and Reactogenicity in Patients With Rheumatic and Musculoskeletal Diseases Following Two-Dose SARS-CoV-2 Messenger RNA Vaccination
    Connolly, Caoilfhionn M.
    Ruddy, Jake A.
    Boyarsky, Brian J.
    Barbur, Iulia
    Werbel, William A.
    Geetha, Duvuru
    Garonzik-Wang, Jacqueline M.
    Segev, Dorry L.
    Christopher-Stine, Lisa
    Paik, Julie J.
    ARTHRITIS & RHEUMATOLOGY, 2022, 74 (01) : 28 - 32
  • [4] Outbreak of SARS-CoV-2 B.1.617.2 (Delta) Variant Infections Among Incarcerated Persons in a Federal Prison - Texas, July-August 2021
    Hagan, Liesl M.
    McCormick, David W.
    Lee, Christine
    Sleweon, Sadia
    Nicolae, Lavinia
    Dixon, Thomas
    Banta, Robert
    Ogle, Isaac
    Young, Cristen
    Dusseau, Charles
    Salmonson, Shawn
    Ogden, Charles
    Godwin, Eric
    Ballom, TeCora
    Ross, Tara
    Browne, Hannah
    Harcourt, Jennifer L.
    Tamin, Azaibi
    Thornburg, Natalie J.
    Kirking, Hannah L.
    Salvatore, Phillip P.
    Tate, Jacqueline E.
    MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT, 2021, 70 (38): : 1349 - 1354
  • [5] Booster Vaccination Decreases 28-Day All-Cause Mortality of the Elderly Hospitalized Due to SARS-CoV-2 Delta Variant
    Muller, Veronika
    Polivka, Lorinc
    Valyi-Nagy, Istvan
    Nagy, Alexandra
    Szekanecz, Zoltan
    Bogos, Krisztina
    Vago, Hajnalka
    Kamondi, Anita
    Fekete, Ferenc
    Szlavik, Janos
    Elek, Jeno
    Surjan, Gyorgy
    Surjan, Orsolya
    Nagy, Peter
    Schaff, Zsuzsa
    Muller, Cecilia
    Kiss, Zoltan
    Kasler, Miklos
    VACCINES, 2022, 10 (07)
  • [6] Tuberculosis following two-dose SARS-CoV-2 vaccination with messenger RNA vaccine (BNT162b2) and inactivated virus vaccine (CoronaVac)
    Li, Xue
    Peng, Kuan
    Cheng, Franco W. T.
    Lam, David C. L.
    Cheung, Ching Lung
    Chui, Celine S. L.
    Lai, Francisco T. T.
    Wan, Eric Y. F.
    Wong, Carlos K. H.
    Ma, Tiantian
    Yum, Samson H. H.
    Chan, Esther W. Y.
    Huang, Jian Dong
    Lau, Chak Sing
    Ip, Mary S. M.
    Wong, Ian C. K.
    JOURNAL OF INFECTION, 2023, 86 (03) : 299 - 302
  • [7] An outbreak caused by the SARS-CoV-2 Delta (B.1.617.2) variant in a care home after partial vaccination with a single dose of the COVID-19 vaccine Vaxzevria, London, England, April 2021
    Williams, Sarah V.
    Vusirikala, Amoolya
    Ladhani, Shamez N.
    De Olano, Elena Fernandez Ruiz
    Iyanger, Nalini
    Aiano, Felicity
    Stoker, Kelly
    Rao, Guduru Gopal
    John, Laurence
    Patel, Bharat
    Andrews, Nick
    Dabrera, Gavin
    Ramsay, Mary
    Brown, Kevin E.
    Bernal, Jamie Lopez
    Saliba, Vanessa
    EUROSURVEILLANCE, 2021, 26 (27)
  • [8] Primary and Secondary Attack Rates by Vaccination Status after a SARS-CoV-2 B.1.617.2 (Delta) Variant Outbreak at a Youth Summer Camp-Texas, June 2021
    Baker, Julia M.
    Shah, Melisa M.
    O'Hegarty, Michelle
    Pomeroy, Mary
    Keiser, Philip
    Ren, Ping
    Weaver, Scott C.
    Maknojia, Sara
    Machado, Rafael R. G.
    Mitchell, Brooke M.
    McConnell, Allan
    Tate, Jacqueline E.
    Kirking, Hannah L.
    JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY, 2022, 11 (12) : 550 - 556
  • [9] Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Outbreak at a College With High Coronavirus Disease 2019 (COVID-19) Vaccination Coverage-Connecticut, August 2021-September 2021
    Bart, Stephen M.
    Curtiss, Christina C.
    Earnest, Rebecca
    Lobe-Costonis, Rachel
    Peterson, Hanna
    McWilliams, Caroline
    Billig, Kendall
    Hadler, James L.
    Grubaugh, Nathan D.
    Arcelus, Victor J.
    Sosa, Lynn E.
    CLINICAL INFECTIOUS DISEASES, 2022, 75 : S243 - S250
  • [10] HUMORAL IMMUNE RESPONSE OF THE ADDITIONAL CHADOX1 NCOV-19 VACCINE FOLLOWING A TWO-DOSE INACTIVATED WHOLE-VIRUS SARS-COV-2 VACCINATION IN PATIENTS ON DIALYSIS
    Kitpermkiat, Rungthiwa
    Bruminhent, Jackrapong
    Setthaudom, Chavachol
    Chuengsaman, Piyatida
    Kiertiburanakul, Sasisopin
    Malathum, Kumthorn
    Assanatham, Montira
    Nongnuch, Arkom
    Phuphuakrat, Angsana
    Chaumdee, Pongsathon
    Janphram, Chitimaporn
    Thotsiri, Sansanee
    Boongird, Sarinya
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2022, 37 : I127 - I127