Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin

被引:88
|
作者
Jambhrunkar, Siddharth [1 ]
Karmakar, Surajit [1 ]
Popat, Amirali [1 ]
Yu, Meihua [1 ]
Yu, Chengzhong [1 ]
机构
[1] Univ Queensland, Australian Inst Bioengn & Nanotechnol, Brisbane, Qld 4072, Australia
来源
RSC ADVANCES | 2014年 / 4卷 / 02期
基金
澳大利亚研究理事会;
关键词
DRUG-DELIVERY SYSTEM; IMPROVING BIOAVAILABILITY; CANCER-THERAPY; APOPTOSIS; MCM-41; BIOCOMPATIBILITY; DEGRADATION; EXPRESSION; STABILITY; RELEASE;
D O I
10.1039/c3ra44257h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Curcumin encapsulated in mesoporous silica nanoparticles showed improved solubility, in vitro release profile and significantly enhanced cell cytotoxicity compared to the pure drug.
引用
收藏
页码:709 / 712
页数:4
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