Body mass index, type 2 diabetes, and left ventricular function

被引:5
|
作者
Musaeus, Katrine Dina [1 ]
Pareek, Manan [2 ,3 ]
机构
[1] Univ Copenhagen, Fac Hlth & Med Sci, Blegdamsvej 3B, DK-2200 Copenhagen N, Denmark
[2] Harvard Med Sch, Brigham & Womens Hosp, Heart & Vasc Ctr, 75 Francis St, Boston, MA 02115 USA
[3] Odense Univ Hosp, Ctr Individualized Med Arterial Dis CIMA, Dept Endocrinol, Cardiovasc & Metab Prevent Clin, Sdr Blvd 29, DK-5000 Odense C, Denmark
来源
关键词
Body mass index; Diabetes mellitus; type; 2; Ventricular dysfunction; left; Ventricular function; INSULIN-RESISTANCE; MORTALITY; ADULTS;
D O I
10.1186/s12933-017-0649-9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A recent study found that among individuals with a preserved left ventricular ejection fraction >= 55%, global longitudinal strain was significantly lower in overweight patients (i.e., body mass index >= 25 kg/m(2)) with, but not in those without, type 2 diabetes mellitus. These results contrast previous observations of body mass index as a significant predictor of incident diastolic dysfunction and increased left ventricular mass index among subjects without prevalent diabetes. We discuss potential explanations for the observed discrepancies and general difficulties associated with cardiovascular risk assessment based on body mass index and related metabolic factors.
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页数:2
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