Selective PI3Kδ Inhibitors as Anti-NASH Agents

被引:0
|
作者
Vakkalanka, Swaroop
Muthuppalaniappan, Meyyappan
Babu, G.
Varanasi, Kanthikiran
Routhu, Kasiviswanath
Nyayapathy, Seeta
Veeraraghavan, Sridhar
Viswanadha, Srikant
Nagaratham, Dhanapalan
机构
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
321-OR
引用
收藏
页码:A84 / A84
页数:1
相关论文
共 50 条
  • [1] Designing selective PI3K inhibitors
    Sarah Crunkhorn
    Nature Reviews Drug Discovery, 2010, 9 : 105 - 105
  • [2] Designing selective PI3K inhibitors
    Crunkhorn, Sarah
    NATURE REVIEWS DRUG DISCOVERY, 2010, 9 (02) : 105 - 105
  • [3] Discovery of Potent and Selective PI3Kγ Inhibitors
    Drew, Samuel L.
    Thomas-Tran, Rhiannon
    Beatty, Joel W.
    Fournier, Jeremy
    Lawson, Kenneth, V
    Miles, Dillon H.
    Mata, Guillaume
    Sharif, Ehesan U.
    Yan, Xuelei
    Mailyan, Artur K.
    Ginn, Elaine
    Chen, Jie
    Wong, Kent
    Soni, Divyank
    Dhanota, Puja
    Chen, Pei-Yu
    Shaqfeh, Stefan G.
    Meleza, Cesar
    Pham, Amber T.
    Chen, Ada
    Zhao, Xiaoning
    Banuelos, Jesus
    Jin, Lixia
    Schindler, Ulrike
    Walters, Matthew J.
    Young, Stephen W.
    Walker, Nigel P.
    Leleti, Manmohan Reddy
    Powers, Jay P.
    Jeffrey, Jenna L.
    JOURNAL OF MEDICINAL CHEMISTRY, 2020, 63 (19) : 11235 - 11257
  • [4] Discovery of novel quinazolinone derivatives as high potent and selective PI3Kδ and PI3Kδ/γ inhibitors
    Ma, Chen-Chen
    Zhang, Cheng-Mei
    Tang, Long-Qian
    Liu, Zhao-Peng
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 151 : 9 - 17
  • [5] Discovery, Optimization, and Evaluation of Potent and Highly Selective PI3Kγ-PI3Kδ Dual Inhibitors
    Jia, Hong
    Dai, Guangxiu
    Su, Weiguo
    Xiao, Kun
    Weng, Jianyang
    Zhang, Zhulin
    Wang, Qing
    Yuan, Tianhai
    Shi, Fuying
    Zhang, Zheng
    Chen, Wei
    Sai, Yang
    Wang, Jian
    Li, Xiong
    Cai, Yu
    Yu, Jun
    Ren, Ping
    Venable, Jennifer
    Rao, Tadimeti
    Edwards, James P.
    Bembenek, Scott D.
    JOURNAL OF MEDICINAL CHEMISTRY, 2019, 62 (10) : 4936 - 4948
  • [6] Development of PI3Kγ selective inhibitors: the strategies and application
    Gu, Dong-Yan
    Zhang, Meng-Meng
    Li, Jia
    Zhou, Yu-Bo
    Sheng, Rong
    ACTA PHARMACOLOGICA SINICA, 2024, 45 (02) : 238 - 247
  • [7] Selective PI3Kδ inhibitors, a review of the patent literature
    Norman, Peter
    EXPERT OPINION ON THERAPEUTIC PATENTS, 2011, 21 (11) : 1773 - 1790
  • [8] Development of novel, selective and irreversible PI3Kδ inhibitors
    Dalton, Samuel
    Campos, Sebastien
    Bush, Jacob
    Thomas, Daniel
    Convery, Maire
    Murphy, John
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
  • [9] PI3K Isoform-Selective Inhibitors in Cancer
    Duncan, Leslie
    Shay, Chloe
    Teng, Yong
    SINGLE-CELL SEQUENCING AND METHYLATION: METHODS AND CLINICAL APPLICATIONS, 2020, 1255 : 165 - 173
  • [10] Optimization of Versatile Oxindoles as Selective PI3Kδ Inhibitors
    Methot, Joey L.
    Achab, Abdelghani
    Christopher, Matthew
    Zhou, Hua
    McGowan, Meredeth A.
    Trotter, B. Wesley
    Fradera, Xavier
    Lesburg, Charles A.
    Goldenblatt, Peter
    Hill, Armetta
    Chen, Dapeng
    Otte, Karin M.
    Augustin, Martin
    Shah, Sanjiv
    Katz, Jason D.
    ACS MEDICINAL CHEMISTRY LETTERS, 2020, 11 (12): : 2461 - 2469