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Steroidal glycosides from Marsdenia tenacissima
被引:4
|作者:
Van Khang, Pham
[1
]
Xu, Ting
[1
]
Xu, Liuxin
[1
]
Zhou, Nannan
[1
]
Hu, Lihong
[1
]
Wang, Rui
[1
]
Ma, Lei
[1
]
机构:
[1] E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab New Drug Design, Shanghai 200237, Peoples R China
关键词:
Marsdenia tenacissi;
Tenacigenin B;
Nitric oxide;
Inhibitory activity;
POLYOXYPREGNANE GLYCOSIDES;
STEMS;
D O I:
10.1016/j.phytol.2015.01.018
中图分类号:
Q94 [植物学];
学科分类号:
071001 ;
摘要:
Three new compounds 1-3 as C-21 steroidal glycosides of diester derivatives of tenacigenin B were isolated from the ethanolic extract of stems of Marsdenia tenacissima. All compounds were prepared and evaluated inhibitory activity of nitric oxide in RAW276.4 macrophages. Compounds 1-3 exhibited inhibitory effects against nitric oxide (NO). (C) 2015 Published by Elsevier B.V. on behalf of Phytochemical Society of Europe.
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页码:54 / 58
页数:5
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