Steroidal glycosides from Marsdenia tenacissima

被引:4
|
作者
Van Khang, Pham [1 ]
Xu, Ting [1 ]
Xu, Liuxin [1 ]
Zhou, Nannan [1 ]
Hu, Lihong [1 ]
Wang, Rui [1 ]
Ma, Lei [1 ]
机构
[1] E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab New Drug Design, Shanghai 200237, Peoples R China
关键词
Marsdenia tenacissi; Tenacigenin B; Nitric oxide; Inhibitory activity; POLYOXYPREGNANE GLYCOSIDES; STEMS;
D O I
10.1016/j.phytol.2015.01.018
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Three new compounds 1-3 as C-21 steroidal glycosides of diester derivatives of tenacigenin B were isolated from the ethanolic extract of stems of Marsdenia tenacissima. All compounds were prepared and evaluated inhibitory activity of nitric oxide in RAW276.4 macrophages. Compounds 1-3 exhibited inhibitory effects against nitric oxide (NO). (C) 2015 Published by Elsevier B.V. on behalf of Phytochemical Society of Europe.
引用
收藏
页码:54 / 58
页数:5
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