Estimation of apoptosis in C6 glioma cells treated with antidepressants

被引：0
|
作者：
Spanova, A
Kovaru, H
Lisa, V
Lukasova, E
Rittich, B
机构：
[1] TECH UNIV,FAC CHEM,BRNO 63700,CZECH REPUBLIC
[2] ACAD SCI CZECH REPUBL,INST ANIM PHYSIOL & GENET,BRNO,CZECH REPUBLIC
[3] CHARLES UNIV,FAC MED 1,PRAGUE,CZECH REPUBLIC
[4] ACAD SCI CZECH REPUBL,INST PHYSIOL,PRAGUE,CZECH REPUBLIC
[5] ACAD SCI CZECH REPUBL,INST BIOPHYS,CS-61265 BRNO,CZECH REPUBLIC
来源：
PHYSIOLOGICAL RESEARCH | 1997年 / 46卷 / 02期
关键词：
glioma cells; antidepressants; DNA fragmentation; apoptosis;
D O I：
暂无
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
Gel electrophoresis of DNA was used for estimation of DNA changes caused in C6 glioma cells by treatment with psychotropic drugs (imipramine, amitryptiline and fluoxetine). Some discrete bands containing a population of short DNA fragments appeared after 1 and 5 days of cultivation. Apoptotic DNA breaks were verified at single cell level using the TUNEL test in cells treated with fluoxetine.
引用
收藏
页码：161 / 164
页数：4
相关论文
共 50 条
  • [1] Detection of apoptosis and phagocytosis in vitro in C6 rat glioma cells treated with tiazofurin
    Piperski, V
    Vracar, M
    Jokanovic, M
    Stukalov, P
    Rakic, L
    APOPTOSIS, 1998, 3 (05) : 345 - 352
  • [2] Detection of apoptosis and phagocytosis in vitro in C6 rat glioma cells treated with tiazofurin
    V. Piperski
    M. Vračar
    M. Jokanović
    P. Stukalov
    L. Rakić
    Apoptosis, 1998, 3 : 345 - 352
  • [3] Delayed induction of apoptosis by ammonia in C6 glioma cells
    Buzanska, L
    Zablocka, B
    Dybel, A
    Domanska-Janik, K
    Albrecht, J
    NEUROCHEMISTRY INTERNATIONAL, 2000, 37 (2-3) : 287 - 297
  • [4] Induction of apoptosis in rat C6 glioma cells by panaxydol
    Hai, Han
    Lin, Qi
    Lu, Yang
    Zhang, Hao
    Yi, Jing
    CELL BIOLOGY INTERNATIONAL, 2007, 31 (07) : 711 - 715
  • [5] Naringenin promote apoptosis in cerebrally implanted C6 glioma cells
    Sabarinathan, Devan
    Mahalakshmi, Palani
    Vanisree, Arambakkam Janardhanam
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 2010, 345 (1-2) : 215 - 222
  • [6] Δ9-tetrahydrocannabinol induces apoptosis in C6 glioma cells
    Sánchez, C
    Galve-Roperh, I
    Canova, C
    Brachet, P
    Guzmán, M
    FEBS LETTERS, 1998, 436 (01) : 6 - 10
  • [7] Naringenin promote apoptosis in cerebrally implanted C6 glioma cells
    Devan Sabarinathan
    Palani Mahalakshmi
    Arambakkam Janardhanam Vanisree
    Molecular and Cellular Biochemistry, 2010, 345 : 215 - 222
  • [8] Phosphatidylserine synthesis in phorbol ester treated glioma C6 cells
    Czarny, M
    Wiktorek, M
    Sabala, P
    Pomorski, P
    Baranska, J
    BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL, 1995, 36 (03): : 659 - 667
  • [9] Osmosignalling in C6 glioma cells
    Sinning, R
    Schliess, F
    Kubitz, R
    Haussinger, D
    FEBS LETTERS, 1997, 400 (02): : 163 - 167
  • [10] Thyroid hormone, a growth factor for C6 glioma cells, reverses resveratrol-induced apoptosis in C6 cells.
    Cao, H. James
    Lin, Hung-Yun
    Lansing, Larry
    Davis, Faith B.
    Tang, Heng-Yuan
    Tong, Fumin
    Hercbergs, Aleck
    Davis, Paul
    CANCER RESEARCH, 2006, 66 (08)
12345